N6-methyladenosine mRNA marking promotes selective translation of regulons required for human erythropoiesis

Erythropoiesis can be regulated by transcriptional, epigenetic, and post-transcriptional mechanisms. Here the authors report that N6-methyladenosine mRNA methyltransferase complex stimulates erythropoiesis by promoting translation of specific mRNAs.

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Autores principales:	Daniel A. Kuppers, Sonali Arora, Yiting Lim, Andrea R. Lim, Lucas M. Carter, Philip D. Corrin, Christopher L. Plaisier, Ryan Basom, Jeffrey J. Delrow, Shiyan Wang, Housheng Hansen He, Beverly Torok-Storb, Andrew C. Hsieh, Patrick J. Paddison
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/47ac3c50e65642a7995551b19d63d3ca
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spelling	oai:doaj.org-article:47ac3c50e65642a7995551b19d63d3ca2021-12-02T15:35:29ZN6-methyladenosine mRNA marking promotes selective translation of regulons required for human erythropoiesis10.1038/s41467-019-12518-62041-1723https://doaj.org/article/47ac3c50e65642a7995551b19d63d3ca2019-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12518-6https://doaj.org/toc/2041-1723Erythropoiesis can be regulated by transcriptional, epigenetic, and post-transcriptional mechanisms. Here the authors report that N6-methyladenosine mRNA methyltransferase complex stimulates erythropoiesis by promoting translation of specific mRNAs.Daniel A. KuppersSonali AroraYiting LimAndrea R. LimLucas M. CarterPhilip D. CorrinChristopher L. PlaisierRyan BasomJeffrey J. DelrowShiyan WangHousheng Hansen HeBeverly Torok-StorbAndrew C. HsiehPatrick J. PaddisonNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Daniel A. Kuppers Sonali Arora Yiting Lim Andrea R. Lim Lucas M. Carter Philip D. Corrin Christopher L. Plaisier Ryan Basom Jeffrey J. Delrow Shiyan Wang Housheng Hansen He Beverly Torok-Storb Andrew C. Hsieh Patrick J. Paddison N6-methyladenosine mRNA marking promotes selective translation of regulons required for human erythropoiesis
description	Erythropoiesis can be regulated by transcriptional, epigenetic, and post-transcriptional mechanisms. Here the authors report that N6-methyladenosine mRNA methyltransferase complex stimulates erythropoiesis by promoting translation of specific mRNAs.
format	article
author	Daniel A. Kuppers Sonali Arora Yiting Lim Andrea R. Lim Lucas M. Carter Philip D. Corrin Christopher L. Plaisier Ryan Basom Jeffrey J. Delrow Shiyan Wang Housheng Hansen He Beverly Torok-Storb Andrew C. Hsieh Patrick J. Paddison
author_facet	Daniel A. Kuppers Sonali Arora Yiting Lim Andrea R. Lim Lucas M. Carter Philip D. Corrin Christopher L. Plaisier Ryan Basom Jeffrey J. Delrow Shiyan Wang Housheng Hansen He Beverly Torok-Storb Andrew C. Hsieh Patrick J. Paddison
author_sort	Daniel A. Kuppers
title	N6-methyladenosine mRNA marking promotes selective translation of regulons required for human erythropoiesis
title_short	N6-methyladenosine mRNA marking promotes selective translation of regulons required for human erythropoiesis
title_full	N6-methyladenosine mRNA marking promotes selective translation of regulons required for human erythropoiesis
title_fullStr	N6-methyladenosine mRNA marking promotes selective translation of regulons required for human erythropoiesis
title_full_unstemmed	N6-methyladenosine mRNA marking promotes selective translation of regulons required for human erythropoiesis
title_sort	n6-methyladenosine mrna marking promotes selective translation of regulons required for human erythropoiesis
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/47ac3c50e65642a7995551b19d63d3ca
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N6-methyladenosine mRNA marking promotes selective translation of regulons required for human erythropoiesis

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