N6-methyladenosine mRNA marking promotes selective translation of regulons required for human erythropoiesis

N6-methyladenosine mRNA marking promotes selective translation of regulons required for human erythropoiesis

Erythropoiesis can be regulated by transcriptional, epigenetic, and post-transcriptional mechanisms. Here the authors report that N6-methyladenosine mRNA methyltransferase complex stimulates erythropoiesis by promoting translation of specific mRNAs.

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Autores principales: Daniel A. Kuppers, Sonali Arora, Yiting Lim, Andrea R. Lim, Lucas M. Carter, Philip D. Corrin, Christopher L. Plaisier, Ryan Basom, Jeffrey J. Delrow, Shiyan Wang, Housheng Hansen He, Beverly Torok-Storb, Andrew C. Hsieh, Patrick J. Paddison
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Science
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Acceso en línea:https://doaj.org/article/47ac3c50e65642a7995551b19d63d3ca
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https://doaj.org/article/47ac3c50e65642a7995551b19d63d3ca

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