Gut–Kidney Axis on Chip for Studying Effects of Antibiotics on Risk of Hemolytic Uremic Syndrome by Shiga Toxin-Producing <i>Escherichia coli</i>

Gut–Kidney Axis on Chip for Studying Effects of Antibiotics on Risk of Hemolytic Uremic Syndrome by Shiga Toxin-Producing <i>Escherichia coli</i>

Shiga toxin-producing <i>Escherichia coli</i> (STEC) infects humans by colonizing the large intestine, and causes kidney damage by secreting Shiga toxins (Stxs). The increased secretion of Shiga toxin 2 (Stx2) by some antibiotics, such as ciprofloxacin (CIP), increases the risk of hemoly...

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Bibliographic Details
Main Authors: Yugyeong Lee, Min-Hyeok Kim, David Rodrigues Alves, Sejoong Kim, Luke P. Lee, Jong Hwan Sung, Sungsu Park
Format: article
Language:EN
Published: MDPI AG 2021
Subjects:
hemolytic–uremic syndrome (HUS)
multi-organ-on-a-chip
<i>Escherichia coli</i> infection
antibiotics
Shiga toxin
Medicine
R
Online Access:https://doaj.org/article/47b4bf36412645b394b055f06cc19efd
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https://doaj.org/article/47b4bf36412645b394b055f06cc19efd

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