Reversal of stress fibre formation by Nitric Oxide mediated RhoA inhibition leads to reduction in the height of preformed thrombi

Abstract Evidence has emerged to suggest that thrombi are dynamic structures with distinct areas of differing platelet activation and inhibition. We hypothesised that Nitric oxide (NO), a platelet inhibitor, can modulate the actin cytoskeleton reversing platelet spreading, and therefore reduce the c...

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Autores principales: L. Atkinson, M. Z. Yusuf, A. Aburima, Y. Ahmed, S. G. Thomas, K. M. Naseem, S. D. J. Calaminus
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/47b80d4fc1b24e3cb0f8f547d9aabf66
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