Reversal of stress fibre formation by Nitric Oxide mediated RhoA inhibition leads to reduction in the height of preformed thrombi

Abstract Evidence has emerged to suggest that thrombi are dynamic structures with distinct areas of differing platelet activation and inhibition. We hypothesised that Nitric oxide (NO), a platelet inhibitor, can modulate the actin cytoskeleton reversing platelet spreading, and therefore reduce the c...

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Auteurs principaux: L. Atkinson, M. Z. Yusuf, A. Aburima, Y. Ahmed, S. G. Thomas, K. M. Naseem, S. D. J. Calaminus
Format: article
Langue:EN
Publié: Nature Portfolio 2018
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Accès en ligne:https://doaj.org/article/47b80d4fc1b24e3cb0f8f547d9aabf66
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