The role of ESCO2, SALL4 and TBX5 genes in the susceptibility to thalidomide teratogenesis
Abstract Thalidomide is widely used for several diseases; however, it causes malformations in embryos exposed during pregnancy. The complete understanding of the mechanisms by which thalidomide affects the embryo development has not yet been obtained. The phenotypic similarity makes TE a phenocopy o...
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Autores principales: | Julia do Amaral Gomes, Thayne Woycinck Kowalski, Lucas Rosa Fraga, Gabriel S. Macedo, Maria Teresa Vieira Sanseverino, Lavínia Schuler-Faccini, Fernanda Sales Luiz Vianna |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2019
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Materias: | |
Acceso en línea: | https://doaj.org/article/47bc5eea5a014c35bbd8994693675834 |
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