The role of ESCO2, SALL4 and TBX5 genes in the susceptibility to thalidomide teratogenesis

Abstract Thalidomide is widely used for several diseases; however, it causes malformations in embryos exposed during pregnancy. The complete understanding of the mechanisms by which thalidomide affects the embryo development has not yet been obtained. The phenotypic similarity makes TE a phenocopy o...

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Autores principales: Julia do Amaral Gomes, Thayne Woycinck Kowalski, Lucas Rosa Fraga, Gabriel S. Macedo, Maria Teresa Vieira Sanseverino, Lavínia Schuler-Faccini, Fernanda Sales Luiz Vianna
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/47bc5eea5a014c35bbd8994693675834
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