The natural sulfoglycolipid derivative SQAP improves the therapeutic efficacy of tissue factor-targeted radioimmunotherapy in the stroma-rich pancreatic cancer model BxPC-3

α-Sulfoquinovosylacyl-1,3-propanediol (SQAP) is a semi-synthetic derivative of natural sulfoglycolipid that sensitizes tumors to external-beam radiotherapy. How SQAP affects internal radiotherapy, however, is not known. Here, we investigated the effects of SQAP for radioimmunotherapy (RIT) targeting...

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Auteurs principaux: Yoichi Takakusagi, Aya Sugyo, Atsushi B. Tsuji, Hitomi Sudo, Masahiro Yasunaga, Yasuhiro Matsumura, Fumio Sugawara, Kengo Sakaguchi, Tatsuya Higashi
Format: article
Langue:EN
Publié: Elsevier 2022
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Accès en ligne:https://doaj.org/article/47bda2ddaee24e27979c80f2bea5f435
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