Selected 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase inhibitors. A look into their use and potential in pre-diabetes and type 2 diabetes

Objectives. This review assesses the comparative safety and efficacy of selected 3-hydroxy-3-methylglutaric acid coenzyme A inhibitors (statins, cinnamic acids. 3-hydroxy-3-methyl glutaric acid) on the pre-onset type 2 diabetes (PT2D) and post-onset type 2 diabetes (T2D)-related cluster of seven fea...

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Autores principales: Barre Douglas Edward, Mizier-Barre Kazimiera Amelia
Formato: article
Lenguaje:EN
Publicado: Sciendo 2021
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Acceso en línea:https://doaj.org/article/47bfd362d0fe4b27882c534ed192c1a5
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spelling oai:doaj.org-article:47bfd362d0fe4b27882c534ed192c1a52021-12-02T17:37:18ZSelected 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase inhibitors. A look into their use and potential in pre-diabetes and type 2 diabetes1336-032910.2478/enr-2021-0020https://doaj.org/article/47bfd362d0fe4b27882c534ed192c1a52021-07-01T00:00:00Zhttps://doi.org/10.2478/enr-2021-0020https://doaj.org/toc/1336-0329Objectives. This review assesses the comparative safety and efficacy of selected 3-hydroxy-3-methylglutaric acid coenzyme A inhibitors (statins, cinnamic acids. 3-hydroxy-3-methyl glutaric acid) on the pre-onset type 2 diabetes (PT2D) and post-onset type 2 diabetes (T2D)-related cluster of seven features (central obesity, hyperglycemia, hypertension, dyslipidemia, pro-thrombosis, oxidation and inflammation).Barre Douglas EdwardMizier-Barre Kazimiera AmeliaSciendoarticlestatinsflaxseed lignan complexcinnamic acids3-hydroxy-3-methylglutaric acid3-hydroxy-3-methylglutaric acid coenzyme a reductase inhibitiontype 2 diabetes mellituscentral obesityhyperglycemiahypertensiondyslipidemiapro-thrombosisoxidation and inflammationDiseases of the endocrine glands. Clinical endocrinologyRC648-665ENEndocrine Regulations, Vol 55, Iss 3, Pp 182-192 (2021)
institution DOAJ
collection DOAJ
language EN
topic statins
flaxseed lignan complex
cinnamic acids
3-hydroxy-3-methylglutaric acid
3-hydroxy-3-methylglutaric acid coenzyme a reductase inhibition
type 2 diabetes mellitus
central obesity
hyperglycemia
hypertension
dyslipidemia
pro-thrombosis
oxidation and inflammation
Diseases of the endocrine glands. Clinical endocrinology
RC648-665
spellingShingle statins
flaxseed lignan complex
cinnamic acids
3-hydroxy-3-methylglutaric acid
3-hydroxy-3-methylglutaric acid coenzyme a reductase inhibition
type 2 diabetes mellitus
central obesity
hyperglycemia
hypertension
dyslipidemia
pro-thrombosis
oxidation and inflammation
Diseases of the endocrine glands. Clinical endocrinology
RC648-665
Barre Douglas Edward
Mizier-Barre Kazimiera Amelia
Selected 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase inhibitors. A look into their use and potential in pre-diabetes and type 2 diabetes
description Objectives. This review assesses the comparative safety and efficacy of selected 3-hydroxy-3-methylglutaric acid coenzyme A inhibitors (statins, cinnamic acids. 3-hydroxy-3-methyl glutaric acid) on the pre-onset type 2 diabetes (PT2D) and post-onset type 2 diabetes (T2D)-related cluster of seven features (central obesity, hyperglycemia, hypertension, dyslipidemia, pro-thrombosis, oxidation and inflammation).
format article
author Barre Douglas Edward
Mizier-Barre Kazimiera Amelia
author_facet Barre Douglas Edward
Mizier-Barre Kazimiera Amelia
author_sort Barre Douglas Edward
title Selected 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase inhibitors. A look into their use and potential in pre-diabetes and type 2 diabetes
title_short Selected 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase inhibitors. A look into their use and potential in pre-diabetes and type 2 diabetes
title_full Selected 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase inhibitors. A look into their use and potential in pre-diabetes and type 2 diabetes
title_fullStr Selected 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase inhibitors. A look into their use and potential in pre-diabetes and type 2 diabetes
title_full_unstemmed Selected 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase inhibitors. A look into their use and potential in pre-diabetes and type 2 diabetes
title_sort selected 3-hydroxy-3-methyl-glutaryl-coenzyme a reductase inhibitors. a look into their use and potential in pre-diabetes and type 2 diabetes
publisher Sciendo
publishDate 2021
url https://doaj.org/article/47bfd362d0fe4b27882c534ed192c1a5
work_keys_str_mv AT barredouglasedward selected3hydroxy3methylglutarylcoenzymeareductaseinhibitorsalookintotheiruseandpotentialinprediabetesandtype2diabetes
AT mizierbarrekazimieraamelia selected3hydroxy3methylglutarylcoenzymeareductaseinhibitorsalookintotheiruseandpotentialinprediabetesandtype2diabetes
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