Management of rheumatoid arthritis during pregnancy: challenges and solutions

Megan L Krause, Ashima Makol Division of Rheumatology, Department of Internal Medicine, Mayo Clinic, MN, USA Abstract: Rheumatoid arthritis, a chronic inflammatory autoimmune disease with significant physical disability, affects women three times more frequently than men, often in their childbearin...

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Autores principales:	Krause ML, Makol A
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2016
Materias:	rheumatoid arthritis pregnancy biologics DMARDs Diseases of the musculoskeletal system RC925-935
Acceso en línea:	https://doaj.org/article/47d70a954f3d45d690ec8b04a7d341e5
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spelling	oai:doaj.org-article:47d70a954f3d45d690ec8b04a7d341e52021-12-02T02:13:25ZManagement of rheumatoid arthritis during pregnancy: challenges and solutions1179-156Xhttps://doaj.org/article/47d70a954f3d45d690ec8b04a7d341e52016-03-01T00:00:00Zhttps://www.dovepress.com/management-of-rheumatoid-arthritis-during-pregnancy-challenges-and-sol-peer-reviewed-article-OARRRhttps://doaj.org/toc/1179-156XMegan L Krause, Ashima Makol Division of Rheumatology, Department of Internal Medicine, Mayo Clinic, MN, USA Abstract: Rheumatoid arthritis, a chronic inflammatory autoimmune disease with significant physical disability, affects women three times more frequently than men, often in their childbearing years. Parenthood decisions can be challenging, often affected by perceptions of their disease state, health care needs, and complex pharmacological treatments. Many women struggle to find adequate information to guide them on pregnancy planning, lactation, and early parenting in relation to their chronic condition. The expanded availability and choice of pharmacotherapies have supported optimal disease control prior to conception and enhanced physical capabilities for women to successfully overcome the challenges of raising children but require a detailed understanding of their risks and safety in the setting of pregnancy and breastfeeding. This review outlines the various situational challenges faced by rheumatologists in providing care to men and women in the reproductive age group interested in starting a family. Up to date evidence-based solutions particularly focusing on the safe use of disease-modifying antirheumatic drugs and biologic response modifiers to assist rheumatologists in the care of pregnant and lactating women with RA are reviewed. Keywords: rheumatoid arthritis, pregnancy, biologics, DMARDsKrause MLMakol ADove Medical Pressarticlerheumatoid arthritispregnancybiologicsDMARDsDiseases of the musculoskeletal systemRC925-935ENOpen Access Rheumatology: Research and Reviews, Vol 2016, Iss Issue 1, Pp 23-36 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	rheumatoid arthritis pregnancy biologics DMARDs Diseases of the musculoskeletal system RC925-935
spellingShingle	rheumatoid arthritis pregnancy biologics DMARDs Diseases of the musculoskeletal system RC925-935 Krause ML Makol A Management of rheumatoid arthritis during pregnancy: challenges and solutions
description	Megan L Krause, Ashima Makol Division of Rheumatology, Department of Internal Medicine, Mayo Clinic, MN, USA Abstract: Rheumatoid arthritis, a chronic inflammatory autoimmune disease with significant physical disability, affects women three times more frequently than men, often in their childbearing years. Parenthood decisions can be challenging, often affected by perceptions of their disease state, health care needs, and complex pharmacological treatments. Many women struggle to find adequate information to guide them on pregnancy planning, lactation, and early parenting in relation to their chronic condition. The expanded availability and choice of pharmacotherapies have supported optimal disease control prior to conception and enhanced physical capabilities for women to successfully overcome the challenges of raising children but require a detailed understanding of their risks and safety in the setting of pregnancy and breastfeeding. This review outlines the various situational challenges faced by rheumatologists in providing care to men and women in the reproductive age group interested in starting a family. Up to date evidence-based solutions particularly focusing on the safe use of disease-modifying antirheumatic drugs and biologic response modifiers to assist rheumatologists in the care of pregnant and lactating women with RA are reviewed. Keywords: rheumatoid arthritis, pregnancy, biologics, DMARDs
format	article
author	Krause ML Makol A
author_facet	Krause ML Makol A
author_sort	Krause ML
title	Management of rheumatoid arthritis during pregnancy: challenges and solutions
title_short	Management of rheumatoid arthritis during pregnancy: challenges and solutions
title_full	Management of rheumatoid arthritis during pregnancy: challenges and solutions
title_fullStr	Management of rheumatoid arthritis during pregnancy: challenges and solutions
title_full_unstemmed	Management of rheumatoid arthritis during pregnancy: challenges and solutions
title_sort	management of rheumatoid arthritis during pregnancy: challenges and solutions
publisher	Dove Medical Press
publishDate	2016
url	https://doaj.org/article/47d70a954f3d45d690ec8b04a7d341e5
work_keys_str_mv	AT krauseml managementofrheumatoidarthritisduringpregnancychallengesandsolutions AT makola managementofrheumatoidarthritisduringpregnancychallengesandsolutions
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Management of rheumatoid arthritis during pregnancy: challenges and solutions

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