Structural basis of myelin-associated glycoprotein adhesion and signalling

Structural basis of myelin-associated glycoprotein adhesion and signalling

Myelin-associated glycoprotein (MAG) maintains myelin-axon spacing. Here, the authors report the crystal structures of the MAG full ectodomain in complex with oligosaccharide, and use additional assays to provide insights into the mechanism of MAG-mediated signalling.

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Detalles Bibliográficos
Autores principales: Matti F. Pronker, Suzanne Lemstra, Joost Snijder, Albert J. R. Heck, Dominique M. E. Thies-Weesie, R. Jeroen Pasterkamp, Bert J. C. Janssen
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
Materias:
Science
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Acceso en línea:https://doaj.org/article/47da9cf46c964aaaa66b8ca1a8ddde26
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