Post-transplantation diabetes mellitus: an overview

This review presents an analysis of clinical and experimental studies related to post-transplantation diabetes mellitus (PTDM) ? a specific complication after solid organ transplantation. A search of the databases eLibrary, PubMed and Scopus using the keywords ?posttransplantation diabetes mellitus?...

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Autores principales: Igor Alexandrovich Sklyanik, Minara Shamkhalovna Shamkhalova, Marina Vladimirovna Shestakova
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RU
Publicado: Endocrinology Research Centre 2015
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spelling oai:doaj.org-article:47e04ff0cda6403e895bb479046692622021-11-14T09:00:19ZPost-transplantation diabetes mellitus: an overview2072-03512072-037810.14341/DM2015220-31https://doaj.org/article/47e04ff0cda6403e895bb479046692622015-06-01T00:00:00Zhttps://www.dia-endojournals.ru/jour/article/view/6985https://doaj.org/toc/2072-0351https://doaj.org/toc/2072-0378This review presents an analysis of clinical and experimental studies related to post-transplantation diabetes mellitus (PTDM) ? a specific complication after solid organ transplantation. A search of the databases eLibrary, PubMed and Scopus using the keywords ?posttransplantation diabetes mellitus?, ?new onset diabetes after transplantation?, ?transplantation? and ?immunosuppression? yielded in 523 results, including four from Russian literature (one original research manuscript). The analysis included original research, reviews, meta-analyses and monographs published not before 2005 in Russian and English. A total of 60 relevant original researches and reviews were included in this review. Diagnostic criteria, disease risk factors and potential pathogenic mechanisms were all considered. The mechanisms of the diabetogenic effect of modern immunosuppressive drugs were analysed. The principles of pre- and post-transplantation screening for PTDM and optimal management strategies for patients with PTDM are presented. The current controversial issues concerning the various aspects of PTDM are discussed.Igor Alexandrovich SklyanikMinara Shamkhalovna ShamkhalovaMarina Vladimirovna ShestakovaEndocrinology Research Centrearticlepost-transplantation diabetes mellitustransplantationnew onset diabetesimmunosuppressive agentscytochrome p-450hypoglycaemic agentsNutritional diseases. Deficiency diseasesRC620-627ENRUСахарный диабет, Vol 18, Iss 2, Pp 20-31 (2015)
institution DOAJ
collection DOAJ
language EN
RU
topic post-transplantation diabetes mellitus
transplantation
new onset diabetes
immunosuppressive agents
cytochrome p-450
hypoglycaemic agents
Nutritional diseases. Deficiency diseases
RC620-627
spellingShingle post-transplantation diabetes mellitus
transplantation
new onset diabetes
immunosuppressive agents
cytochrome p-450
hypoglycaemic agents
Nutritional diseases. Deficiency diseases
RC620-627
Igor Alexandrovich Sklyanik
Minara Shamkhalovna Shamkhalova
Marina Vladimirovna Shestakova
Post-transplantation diabetes mellitus: an overview
description This review presents an analysis of clinical and experimental studies related to post-transplantation diabetes mellitus (PTDM) ? a specific complication after solid organ transplantation. A search of the databases eLibrary, PubMed and Scopus using the keywords ?posttransplantation diabetes mellitus?, ?new onset diabetes after transplantation?, ?transplantation? and ?immunosuppression? yielded in 523 results, including four from Russian literature (one original research manuscript). The analysis included original research, reviews, meta-analyses and monographs published not before 2005 in Russian and English. A total of 60 relevant original researches and reviews were included in this review. Diagnostic criteria, disease risk factors and potential pathogenic mechanisms were all considered. The mechanisms of the diabetogenic effect of modern immunosuppressive drugs were analysed. The principles of pre- and post-transplantation screening for PTDM and optimal management strategies for patients with PTDM are presented. The current controversial issues concerning the various aspects of PTDM are discussed.
format article
author Igor Alexandrovich Sklyanik
Minara Shamkhalovna Shamkhalova
Marina Vladimirovna Shestakova
author_facet Igor Alexandrovich Sklyanik
Minara Shamkhalovna Shamkhalova
Marina Vladimirovna Shestakova
author_sort Igor Alexandrovich Sklyanik
title Post-transplantation diabetes mellitus: an overview
title_short Post-transplantation diabetes mellitus: an overview
title_full Post-transplantation diabetes mellitus: an overview
title_fullStr Post-transplantation diabetes mellitus: an overview
title_full_unstemmed Post-transplantation diabetes mellitus: an overview
title_sort post-transplantation diabetes mellitus: an overview
publisher Endocrinology Research Centre
publishDate 2015
url https://doaj.org/article/47e04ff0cda6403e895bb47904669262
work_keys_str_mv AT igoralexandrovichsklyanik posttransplantationdiabetesmellitusanoverview
AT minarashamkhalovnashamkhalova posttransplantationdiabetesmellitusanoverview
AT marinavladimirovnashestakova posttransplantationdiabetesmellitusanoverview
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