Targeted Delivery of Therapeutic Gas by Microbubbles

Gas therapy is a new therapeutic method that has been developed in recent years and shows great clinical prospects for the treatment of tumours and cardiovascular, nerve, and immune system diseases. Therapeutic gases, including oxygen, hydrogen, nitric oxide, hydrogen sulfide, xenon, and other bioac...

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Autor principal:	Lingling Xu, MM, Yihan Chen, MM, Qiaofeng Jin, PhD, Li Zhang, MD, Wenpei Fu, BS, Shan Lin, MM, Ling Lin, BS, Rui Wang, BS, Dandan Chen, MM, Zhengyang Han, MM, Mingxing Xie, MD, Yali Yang, MD
Formato:	article
Lenguaje:	EN
Publicado:	Editorial Office of Advanced Ultrasound in Diagnosis and Therapy 2021
Materias:	\|therapeutic gas\|ultrasound microbubbles\|targeted delivery Medical technology R855-855.5 Medicine R
Acceso en línea:	https://doaj.org/article/47e772532c2b4d1b93c76414dc5563c4
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spelling	oai:doaj.org-article:47e772532c2b4d1b93c76414dc5563c42021-11-05T08:34:43ZTargeted Delivery of Therapeutic Gas by Microbubbles2576-251610.37015/AUDT.2021.200059https://doaj.org/article/47e772532c2b4d1b93c76414dc5563c42021-09-01T00:00:00Zhttp://www.journaladvancedultrasound.com:81/fileup/2576-2516/PDF/1630472657273-1596084755.pdfhttps://doaj.org/toc/2576-2516Gas therapy is a new therapeutic method that has been developed in recent years and shows great clinical prospects for the treatment of tumours and cardiovascular, nerve, and immune system diseases. Therapeutic gases, including oxygen, hydrogen, nitric oxide, hydrogen sulfide, xenon, and other bioactive gases are involved in modulating cell signaling pathways and have important physiological functions with substantial therapeutic potential. However, their precise delivery remains a major challenge. Recently, researchers began to use ultrasound to trigger microbubbles that have encapsulated these gases for intravenous administration. This not only enhances the contrast of ultrasound imaging, but also precisely releases gases in the targeted area using ultrasound-targeted microbubble destruction. This article reviews the latest advances in the use of microbubbles to load therapeutic gases for the treatment of diseases.Lingling Xu, MM, Yihan Chen, MM, Qiaofeng Jin, PhD, Li Zhang, MD, Wenpei Fu, BS, Shan Lin, MM, Ling Lin, BS, Rui Wang, BS, Dandan Chen, MM, Zhengyang Han, MM, Mingxing Xie, MD, Yali Yang, MDEditorial Office of Advanced Ultrasound in Diagnosis and Therapyarticle\|therapeutic gas\|ultrasound microbubbles\|targeted deliveryMedical technologyR855-855.5MedicineRENAdvanced Ultrasound in Diagnosis and Therapy, Vol 5, Iss 3, Pp 173-182 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	\|therapeutic gas\|ultrasound microbubbles\|targeted delivery Medical technology R855-855.5 Medicine R
spellingShingle	\|therapeutic gas\|ultrasound microbubbles\|targeted delivery Medical technology R855-855.5 Medicine R Lingling Xu, MM, Yihan Chen, MM, Qiaofeng Jin, PhD, Li Zhang, MD, Wenpei Fu, BS, Shan Lin, MM, Ling Lin, BS, Rui Wang, BS, Dandan Chen, MM, Zhengyang Han, MM, Mingxing Xie, MD, Yali Yang, MD Targeted Delivery of Therapeutic Gas by Microbubbles
description	Gas therapy is a new therapeutic method that has been developed in recent years and shows great clinical prospects for the treatment of tumours and cardiovascular, nerve, and immune system diseases. Therapeutic gases, including oxygen, hydrogen, nitric oxide, hydrogen sulfide, xenon, and other bioactive gases are involved in modulating cell signaling pathways and have important physiological functions with substantial therapeutic potential. However, their precise delivery remains a major challenge. Recently, researchers began to use ultrasound to trigger microbubbles that have encapsulated these gases for intravenous administration. This not only enhances the contrast of ultrasound imaging, but also precisely releases gases in the targeted area using ultrasound-targeted microbubble destruction. This article reviews the latest advances in the use of microbubbles to load therapeutic gases for the treatment of diseases.
format	article
author	Lingling Xu, MM, Yihan Chen, MM, Qiaofeng Jin, PhD, Li Zhang, MD, Wenpei Fu, BS, Shan Lin, MM, Ling Lin, BS, Rui Wang, BS, Dandan Chen, MM, Zhengyang Han, MM, Mingxing Xie, MD, Yali Yang, MD
author_facet	Lingling Xu, MM, Yihan Chen, MM, Qiaofeng Jin, PhD, Li Zhang, MD, Wenpei Fu, BS, Shan Lin, MM, Ling Lin, BS, Rui Wang, BS, Dandan Chen, MM, Zhengyang Han, MM, Mingxing Xie, MD, Yali Yang, MD
author_sort	Lingling Xu, MM, Yihan Chen, MM, Qiaofeng Jin, PhD, Li Zhang, MD, Wenpei Fu, BS, Shan Lin, MM, Ling Lin, BS, Rui Wang, BS, Dandan Chen, MM, Zhengyang Han, MM, Mingxing Xie, MD, Yali Yang, MD
title	Targeted Delivery of Therapeutic Gas by Microbubbles
title_short	Targeted Delivery of Therapeutic Gas by Microbubbles
title_full	Targeted Delivery of Therapeutic Gas by Microbubbles
title_fullStr	Targeted Delivery of Therapeutic Gas by Microbubbles
title_full_unstemmed	Targeted Delivery of Therapeutic Gas by Microbubbles
title_sort	targeted delivery of therapeutic gas by microbubbles
publisher	Editorial Office of Advanced Ultrasound in Diagnosis and Therapy
publishDate	2021
url	https://doaj.org/article/47e772532c2b4d1b93c76414dc5563c4
work_keys_str_mv	AT linglingxummyihanchenmmqiaofengjinphdlizhangmdwenpeifubsshanlinmmlinglinbsruiwangbsdandanchenmmzhengyanghanmmmingxingxiemdyaliyangmd targeteddeliveryoftherapeuticgasbymicrobubbles
_version_	1718444466386239488

Targeted Delivery of Therapeutic Gas by Microbubbles

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