tmem33 is essential for VEGF-mediated endothelial calcium oscillations and angiogenesis
Calcium signalling downstream of VEGF is essential for VEGF-induced angiogenesis. Here Savage et al. show that Transmembrane Protein 33 (TMEM33) is required for angiogenesis and the endothelial calcium response to VEGF, revealing a function for TMEM33 in multicellular organisms.
Saved in:
Main Authors: | Aaron M. Savage, Sathishkumar Kurusamy, Yan Chen, Zhen Jiang, Karishma Chhabria, Ryan B. MacDonald, Hyejeong R. Kim, Heather L. Wilson, Fredericus J. M. van Eeden, Angel L. Armesilla, Timothy J. A. Chico, Robert N. Wilkinson |
---|---|
Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2019
|
Subjects: | |
Online Access: | https://doaj.org/article/47f0ef6f17ce4a149e51a23dc2a30f3c |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
TMEM33 regulates intracellular calcium homeostasis in renal tubular epithelial cells
by: Malika Arhatte, et al.
Published: (2019) -
Dynamic alterations in decoy VEGF receptor-1 stability regulate angiogenesis
by: Joshua M. Boucher, et al.
Published: (2017) -
VEGF amplifies transcription through ETS1 acetylation to enable angiogenesis
by: Jiahuan Chen, et al.
Published: (2017) -
The Bartonella autotransporter BafA activates the host VEGF pathway to drive angiogenesis
by: Kentaro Tsukamoto, et al.
Published: (2020) -
Exercise induces cerebral VEGF and angiogenesis via the lactate receptor HCAR1
by: Cecilie Morland, et al.
Published: (2017)