tmem33 is essential for VEGF-mediated endothelial calcium oscillations and angiogenesis
Calcium signalling downstream of VEGF is essential for VEGF-induced angiogenesis. Here Savage et al. show that Transmembrane Protein 33 (TMEM33) is required for angiogenesis and the endothelial calcium response to VEGF, revealing a function for TMEM33 in multicellular organisms.
Enregistré dans:
Auteurs principaux: | Aaron M. Savage, Sathishkumar Kurusamy, Yan Chen, Zhen Jiang, Karishma Chhabria, Ryan B. MacDonald, Hyejeong R. Kim, Heather L. Wilson, Fredericus J. M. van Eeden, Angel L. Armesilla, Timothy J. A. Chico, Robert N. Wilkinson |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2019
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/47f0ef6f17ce4a149e51a23dc2a30f3c |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
TMEM33 regulates intracellular calcium homeostasis in renal tubular epithelial cells
par: Malika Arhatte, et autres
Publié: (2019) -
Dynamic alterations in decoy VEGF receptor-1 stability regulate angiogenesis
par: Joshua M. Boucher, et autres
Publié: (2017) -
VEGF amplifies transcription through ETS1 acetylation to enable angiogenesis
par: Jiahuan Chen, et autres
Publié: (2017) -
The Bartonella autotransporter BafA activates the host VEGF pathway to drive angiogenesis
par: Kentaro Tsukamoto, et autres
Publié: (2020) -
Exercise induces cerebral VEGF and angiogenesis via the lactate receptor HCAR1
par: Cecilie Morland, et autres
Publié: (2017)