Bioactive electrospun scaffolds for wound healing applications: A comprehensive review

Skin tissue engineering is a promising approach to resorb skin layers and regenerate skin appendages through biomedical scaffold design. A plethora of techniques have been employed to fabricate clinically effective scaffolds among which electrospinning(ES) has gained tremendous attention due to its...

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Autores principales:	Yasamin Pesaran Afsharian, Mostafa Rahimnejad
Formato:	article
Lenguaje:	EN
Publicado:	Elsevier 2021
Materias:	Electrospining Electrospun dressing Biofunctionalization Wound healing process Polymers and polymer manufacture TP1080-1185
Acceso en línea:	https://doaj.org/article/481a6f38cb53406ead2fe27c583a581e
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id	oai:doaj.org-article:481a6f38cb53406ead2fe27c583a581e
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spelling	oai:doaj.org-article:481a6f38cb53406ead2fe27c583a581e2021-11-24T04:24:51ZBioactive electrospun scaffolds for wound healing applications: A comprehensive review0142-941810.1016/j.polymertesting.2020.106952https://doaj.org/article/481a6f38cb53406ead2fe27c583a581e2021-01-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S0142941820321814https://doaj.org/toc/0142-9418Skin tissue engineering is a promising approach to resorb skin layers and regenerate skin appendages through biomedical scaffold design. A plethora of techniques have been employed to fabricate clinically effective scaffolds among which electrospinning(ES) has gained tremendous attention due to its outstanding potential in fabrication of nanoscale structures similar to the native extracellular matrix (ECM). Furthermore, electrospun dressings open many opportunities to enable delivery of drugs and bioactive agents to the wound site. Given promising physical and biochemical signaling cues, ES technology has found extensive applications for providing a template and extracellular environment to promote cellular functions and to restore damaged tissue. In this review, we discuss recently developed bioactive electrospun dressings that have yielded effective acute and chronic wound treatment and tissue development. Furthermore, we introduce requirements of electrospun dressings to navigate excellent scaffold design.Yasamin Pesaran AfsharianMostafa RahimnejadElsevierarticleElectrospiningElectrospun dressingBiofunctionalizationWound healing processPolymers and polymer manufactureTP1080-1185ENPolymer Testing, Vol 93, Iss , Pp 106952- (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Electrospining Electrospun dressing Biofunctionalization Wound healing process Polymers and polymer manufacture TP1080-1185
spellingShingle	Electrospining Electrospun dressing Biofunctionalization Wound healing process Polymers and polymer manufacture TP1080-1185 Yasamin Pesaran Afsharian Mostafa Rahimnejad Bioactive electrospun scaffolds for wound healing applications: A comprehensive review
description	Skin tissue engineering is a promising approach to resorb skin layers and regenerate skin appendages through biomedical scaffold design. A plethora of techniques have been employed to fabricate clinically effective scaffolds among which electrospinning(ES) has gained tremendous attention due to its outstanding potential in fabrication of nanoscale structures similar to the native extracellular matrix (ECM). Furthermore, electrospun dressings open many opportunities to enable delivery of drugs and bioactive agents to the wound site. Given promising physical and biochemical signaling cues, ES technology has found extensive applications for providing a template and extracellular environment to promote cellular functions and to restore damaged tissue. In this review, we discuss recently developed bioactive electrospun dressings that have yielded effective acute and chronic wound treatment and tissue development. Furthermore, we introduce requirements of electrospun dressings to navigate excellent scaffold design.
format	article
author	Yasamin Pesaran Afsharian Mostafa Rahimnejad
author_facet	Yasamin Pesaran Afsharian Mostafa Rahimnejad
author_sort	Yasamin Pesaran Afsharian
title	Bioactive electrospun scaffolds for wound healing applications: A comprehensive review
title_short	Bioactive electrospun scaffolds for wound healing applications: A comprehensive review
title_full	Bioactive electrospun scaffolds for wound healing applications: A comprehensive review
title_fullStr	Bioactive electrospun scaffolds for wound healing applications: A comprehensive review
title_full_unstemmed	Bioactive electrospun scaffolds for wound healing applications: A comprehensive review
title_sort	bioactive electrospun scaffolds for wound healing applications: a comprehensive review
publisher	Elsevier
publishDate	2021
url	https://doaj.org/article/481a6f38cb53406ead2fe27c583a581e
work_keys_str_mv	AT yasaminpesaranafsharian bioactiveelectrospunscaffoldsforwoundhealingapplicationsacomprehensivereview AT mostafarahimnejad bioactiveelectrospunscaffoldsforwoundhealingapplicationsacomprehensivereview
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Bioactive electrospun scaffolds for wound healing applications: A comprehensive review

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