The effects of the miR-21/SMAD7/TGF-β pathway on Th17 cell differentiation in COPD
Abstract Chronic obstructive pulmonary disease (COPD) is a complex disease with multiple etiologies, while smoking is the most established one. The present study investigated the modulation of T-helper 17 (Th17) cell differentiation by the miR-21/Smad7/TGF-β pathway, and their roles in COPD. Lung ti...
Guardado en:
Autores principales: | Shengyang He, Shenghua Sun, Junjuan Lu, Lili Chen, Xiang Mei, Liqiu Li, Zhengpeng Zeng, Mubin Zhong, Lihua Xie |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/482afa0e19274b279914fab03e5ee907 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Concern about: Echinacoside exerts anti-tumor activity via the miR-503-3p/TGF-β1/Smad aixs in liver cancer
por: Jiong Lin
Publicado: (2021) -
MiRNA-21 Regulates Bronchial Epithelial Cell Proliferation by Activating Tgfβ1/Smad Signaling Pathway and Its Correlation with Asthma Severity in Children
por: Yang Kang, et al.
Publicado: (2021) -
Epigenetic Modulation of Class-Switch DNA Recombination to IgA by miR-146a Through Downregulation of Smad2, Smad3 and Smad4
por: Paolo Casali, et al.
Publicado: (2021) -
miR-17 acts as a tumor suppressor by negatively regulating the miR-17-92 cluster
por: Yan Sweat, et al.
Publicado: (2021) -
Enhancement of Th1/Th17 inflammation by TRIM21 in Behçet’s disease
por: Yuri Ahn, et al.
Publicado: (2017)