The Effect of Female Pheromone on the Functional State of Young Men

Introduction. Modern studies show that the presentation of smell of female mice before male mice infection with the influenza virus activates non-specific immune response which protects male mice from infection of the upper respiratory tract and reducing their mortality. However the researches have...

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Autores principales:	Nadezhda A. Litvinova, Alena V. Bedareva, Ksenia Yu. Zubrikova
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2019
Materias:	acute respiratory diseases allergic diseases osmopherine hormones immunoglobulins leukocyte formula Science Q
Acceso en línea:	https://doaj.org/article/482b8982712e45be86ac00e77dcc8bfc
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spelling	oai:doaj.org-article:482b8982712e45be86ac00e77dcc8bfc2021-11-23T06:14:41ZThe Effect of Female Pheromone on the Functional State of Young Men2541-94202587-959610.29413/ABS.2019-4.1.8https://doaj.org/article/482b8982712e45be86ac00e77dcc8bfc2019-04-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/1978https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596Introduction. Modern studies show that the presentation of smell of female mice before male mice infection with the influenza virus activates non-specific immune response which protects male mice from infection of the upper respiratory tract and reducing their mortality. However the researches have not studied the adaptive effect of female sexual pheromone on men.The aim of this work was to study the effect of odor of synthetic analogue of natural female pheromone (Osmopherine) on the functional state of young men often suffering from acute respiratory infections (ARI) and allergic diseases.Materials and methods. We studied four-week effect of Osmopherine on the psycho-emotional state, the concentration of hormones (testosterone, cortisol) and immunoglobulins (sIgA, total IgG), the percentage of leukocytes in the blood and the individual smell of young men, who have ARI more than 4 times a year or an allergic disease. The study involved 117 boys aged 19–23 years. Olfactory testing of individual odor samples of young men was carried out by young women (n = 32) aged 18–22 years.Results. It was found that female pheromone has a positive effect on the functional state of men with different immune systems. However its effect is caused by the pathogenesis of the disease. Application of Osmopherine in men with reduced immunity causes an increased activity, improved mood, reduced anxiety and stabilized testosterone level. Men with allergic diseases did not have the same effect. A significant 2 times decrease in the content of eosinophils was found, which indirectly indicates the decrease in the activity of the delayed phase of allergic reactions of immediate type.Conclusion. The immune system functions according to its internal laws and programs. However its activity for the benefit of the whole body is integrated and regulated by the nervous and endocrine systems. Therefore modulating effect on the functioning of the immune system can be mediated through the presentation of pheromones.Nadezhda A. LitvinovaAlena V. BedarevaKsenia Yu. ZubrikovaScientific Сentre for Family Health and Human Reproduction Problemsarticleacute respiratory diseasesallergic diseasesosmopherinehormonesimmunoglobulinsleukocyte formulaScienceQRUActa Biomedica Scientifica, Vol 4, Iss 1, Pp 50-58 (2019)
institution	DOAJ
collection	DOAJ
language	RU
topic	acute respiratory diseases allergic diseases osmopherine hormones immunoglobulins leukocyte formula Science Q
spellingShingle	acute respiratory diseases allergic diseases osmopherine hormones immunoglobulins leukocyte formula Science Q Nadezhda A. Litvinova Alena V. Bedareva Ksenia Yu. Zubrikova The Effect of Female Pheromone on the Functional State of Young Men
description	Introduction. Modern studies show that the presentation of smell of female mice before male mice infection with the influenza virus activates non-specific immune response which protects male mice from infection of the upper respiratory tract and reducing their mortality. However the researches have not studied the adaptive effect of female sexual pheromone on men.The aim of this work was to study the effect of odor of synthetic analogue of natural female pheromone (Osmopherine) on the functional state of young men often suffering from acute respiratory infections (ARI) and allergic diseases.Materials and methods. We studied four-week effect of Osmopherine on the psycho-emotional state, the concentration of hormones (testosterone, cortisol) and immunoglobulins (sIgA, total IgG), the percentage of leukocytes in the blood and the individual smell of young men, who have ARI more than 4 times a year or an allergic disease. The study involved 117 boys aged 19–23 years. Olfactory testing of individual odor samples of young men was carried out by young women (n = 32) aged 18–22 years.Results. It was found that female pheromone has a positive effect on the functional state of men with different immune systems. However its effect is caused by the pathogenesis of the disease. Application of Osmopherine in men with reduced immunity causes an increased activity, improved mood, reduced anxiety and stabilized testosterone level. Men with allergic diseases did not have the same effect. A significant 2 times decrease in the content of eosinophils was found, which indirectly indicates the decrease in the activity of the delayed phase of allergic reactions of immediate type.Conclusion. The immune system functions according to its internal laws and programs. However its activity for the benefit of the whole body is integrated and regulated by the nervous and endocrine systems. Therefore modulating effect on the functioning of the immune system can be mediated through the presentation of pheromones.
format	article
author	Nadezhda A. Litvinova Alena V. Bedareva Ksenia Yu. Zubrikova
author_facet	Nadezhda A. Litvinova Alena V. Bedareva Ksenia Yu. Zubrikova
author_sort	Nadezhda A. Litvinova
title	The Effect of Female Pheromone on the Functional State of Young Men
title_short	The Effect of Female Pheromone on the Functional State of Young Men
title_full	The Effect of Female Pheromone on the Functional State of Young Men
title_fullStr	The Effect of Female Pheromone on the Functional State of Young Men
title_full_unstemmed	The Effect of Female Pheromone on the Functional State of Young Men
title_sort	effect of female pheromone on the functional state of young men
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2019
url	https://doaj.org/article/482b8982712e45be86ac00e77dcc8bfc
work_keys_str_mv	AT nadezhdaalitvinova theeffectoffemalepheromoneonthefunctionalstateofyoungmen AT alenavbedareva theeffectoffemalepheromoneonthefunctionalstateofyoungmen AT kseniayuzubrikova theeffectoffemalepheromoneonthefunctionalstateofyoungmen AT nadezhdaalitvinova effectoffemalepheromoneonthefunctionalstateofyoungmen AT alenavbedareva effectoffemalepheromoneonthefunctionalstateofyoungmen AT kseniayuzubrikova effectoffemalepheromoneonthefunctionalstateofyoungmen
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The Effect of Female Pheromone on the Functional State of Young Men

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