Lack of Association between the <italic toggle="yes">Tlr4</italic> (<italic toggle="yes">Lps<sup>d</sup>/Lps<sup>d</sup></italic>) Genotype and Increased Susceptibility to <named-content content-type="genus-species">Escherichia coli</named-content> Bladder Infections in Female C3H/HeJ Mice

Lack of Association between the <italic toggle="yes">Tlr4</italic> (<italic toggle="yes">Lps<sup>d</sup>/Lps<sup>d</sup></italic>) Genotype and Increased Susceptibility to <named-content content-type="genus-species">Escherichia coli</named-content> Bladder Infections in Female C3H/HeJ Mice

ABSTRACT Toll-like receptor 4 is thought to have a primary role in host defense against Escherichia coli bladder colonization, based on mouse models of urinary tract infection using C3H/HeJ female mice. This strain carries a point mutation in the Tlr4 gene, which renders the mice unresponsive to lip...

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Autores principales: Kaleigh A. Suhs, Brodie R. Marthaler, Rodney A. Welch, Walter J. Hopkins
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2011
Materias:
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/4838b0b1b4b742548915a17755976eea
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