Digital expression profiling identifies RUNX2, CDC5L, MDM2, RECQL4, and CDK4 as potential predictive biomarkers for neo-adjuvant chemotherapy response in paediatric osteosarcoma.
Osteosarcoma is the most common malignancy of bone, and occurs most frequently in children and adolescents. Currently, the most reliable technique for determining a patients' prognosis is measurement of histopathologic tumor necrosis following pre-operative neo-adjuvant chemotherapy. Unfavourab...
Guardado en:
Autores principales: | Jeffrey W Martin, Susan Chilton-MacNeill, Madhuri Koti, Andre J van Wijnen, Jeremy A Squire, Maria Zielenska |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2014
|
Materias: | |
Acceso en línea: | https://doaj.org/article/4841ba27bddf43929b23acdbdd57ee4b |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
MDM2–MDM4 molecular interaction investigated by atomic force spectroscopy and surface plasmon resonance
por: Moscetti I, et al.
Publicado: (2016) -
Identification of ETV6-RUNX1-like and DUX4-rearranged subtypes in paediatric B-cell precursor acute lymphoblastic leukaemia
por: Henrik Lilljebjörn, et al.
Publicado: (2016) -
CDK6 inhibits white to beige fat transition by suppressing RUNX1
por: Xiaoli Hou, et al.
Publicado: (2018) -
Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair
por: Huiming Lu, et al.
Publicado: (2017) -
Clinical CDK4/6 inhibitors induce selective and immediate dissociation of p21 from cyclin D-CDK4 to inhibit CDK2
por: Lindsey R. Pack, et al.
Publicado: (2021)