CCN1 is an opsonin for bacterial clearance and a direct activator of Toll-like receptor signaling
CCN1 is a matricellular protein with a variety of functions, including an effect on wound healing and an association with inflammation. Here, the authors identify a possible mechanism by showing that CCN1 mediates the clearance of bacterial infections in mice and activates TLR signalling.
Guardado en:
Autores principales: | Joon-Il Jun, Lester F. Lau |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
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Materias: | |
Acceso en línea: | https://doaj.org/article/484bcf6fc0ac4f8cace309d830686ffe |
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