CCN1 is an opsonin for bacterial clearance and a direct activator of Toll-like receptor signaling

CCN1 is a matricellular protein with a variety of functions, including an effect on wound healing and an association with inflammation. Here, the authors identify a possible mechanism by showing that CCN1 mediates the clearance of bacterial infections in mice and activates TLR signalling.

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Bibliographic Details
Main Authors: Joon-Il Jun, Lester F. Lau
Format: article
Language:EN
Published: Nature Portfolio 2020
Subjects:
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Online Access:https://doaj.org/article/484bcf6fc0ac4f8cace309d830686ffe
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