The development of microfabricated solenoids with magnetic cores for micromagnetic neural stimulation
Abstract Electrical stimulation via invasive microelectrodes is commonly used to treat a wide range of neurological and psychiatric conditions. Despite its remarkable success, the stimulation performance is not sustainable since the electrodes become encapsulated by gliosis due to foreign body react...
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Nature Publishing Group
2021
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oai:doaj.org-article:48579a130be8451a824fecf303dce07a2021-11-14T12:10:00ZThe development of microfabricated solenoids with magnetic cores for micromagnetic neural stimulation10.1038/s41378-021-00320-82055-7434https://doaj.org/article/48579a130be8451a824fecf303dce07a2021-11-01T00:00:00Zhttps://doi.org/10.1038/s41378-021-00320-8https://doaj.org/toc/2055-7434Abstract Electrical stimulation via invasive microelectrodes is commonly used to treat a wide range of neurological and psychiatric conditions. Despite its remarkable success, the stimulation performance is not sustainable since the electrodes become encapsulated by gliosis due to foreign body reactions. Magnetic stimulation overcomes these limitations by eliminating the need for a metal-electrode contact. Here, we demonstrate a novel microfabricated solenoid inductor (80 µm × 40 µm) with a magnetic core that can activate neuronal tissue. The characterization and proof-of-concept of the device raise the possibility that micromagnetic stimulation solenoids that are small enough to be implanted within the brain may prove to be an effective alternative to existing electrode-based stimulation devices for chronic neural interfacing applications.Adam KhalifaMohsen ZaeimbashiTony X. ZhouSeyed Mahdi AbrishamiNeville SunSeunghyun ParkTamara ŠumaracJason QuInbar ZoharAmir YacobySydney CashNian X. SunNature Publishing GrouparticleTechnologyTEngineering (General). Civil engineering (General)TA1-2040ENMicrosystems & Nanoengineering, Vol 7, Iss 1, Pp 1-10 (2021) |
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DOAJ |
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DOAJ |
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EN |
| topic |
Technology T Engineering (General). Civil engineering (General) TA1-2040 |
| spellingShingle |
Technology T Engineering (General). Civil engineering (General) TA1-2040 Adam Khalifa Mohsen Zaeimbashi Tony X. Zhou Seyed Mahdi Abrishami Neville Sun Seunghyun Park Tamara Šumarac Jason Qu Inbar Zohar Amir Yacoby Sydney Cash Nian X. Sun The development of microfabricated solenoids with magnetic cores for micromagnetic neural stimulation |
| description |
Abstract Electrical stimulation via invasive microelectrodes is commonly used to treat a wide range of neurological and psychiatric conditions. Despite its remarkable success, the stimulation performance is not sustainable since the electrodes become encapsulated by gliosis due to foreign body reactions. Magnetic stimulation overcomes these limitations by eliminating the need for a metal-electrode contact. Here, we demonstrate a novel microfabricated solenoid inductor (80 µm × 40 µm) with a magnetic core that can activate neuronal tissue. The characterization and proof-of-concept of the device raise the possibility that micromagnetic stimulation solenoids that are small enough to be implanted within the brain may prove to be an effective alternative to existing electrode-based stimulation devices for chronic neural interfacing applications. |
| format |
article |
| author |
Adam Khalifa Mohsen Zaeimbashi Tony X. Zhou Seyed Mahdi Abrishami Neville Sun Seunghyun Park Tamara Šumarac Jason Qu Inbar Zohar Amir Yacoby Sydney Cash Nian X. Sun |
| author_facet |
Adam Khalifa Mohsen Zaeimbashi Tony X. Zhou Seyed Mahdi Abrishami Neville Sun Seunghyun Park Tamara Šumarac Jason Qu Inbar Zohar Amir Yacoby Sydney Cash Nian X. Sun |
| author_sort |
Adam Khalifa |
| title |
The development of microfabricated solenoids with magnetic cores for micromagnetic neural stimulation |
| title_short |
The development of microfabricated solenoids with magnetic cores for micromagnetic neural stimulation |
| title_full |
The development of microfabricated solenoids with magnetic cores for micromagnetic neural stimulation |
| title_fullStr |
The development of microfabricated solenoids with magnetic cores for micromagnetic neural stimulation |
| title_full_unstemmed |
The development of microfabricated solenoids with magnetic cores for micromagnetic neural stimulation |
| title_sort |
development of microfabricated solenoids with magnetic cores for micromagnetic neural stimulation |
| publisher |
Nature Publishing Group |
| publishDate |
2021 |
| url |
https://doaj.org/article/48579a130be8451a824fecf303dce07a |
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