Whole Exome Sequencing to Identify Genetic Variants Associated with Raised Atherosclerotic Lesions in Young Persons

Whole Exome Sequencing to Identify Genetic Variants Associated with Raised Atherosclerotic Lesions in Young Persons

Abstract We investigated the influence of genetic variants on atherosclerosis using whole exome sequencing in cases and controls from the autopsy study “Pathobiological Determinants of Atherosclerosis in Youth (PDAY)”. We identified a PDAY case group with the highest total amounts of raised lesions...

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Main Authors: James E. Hixson, Goo Jun, Lawrence C. Shimmin, Yizhi Wang, Guoqiang Yu, Chunhong Mao, Andrew S. Warren, Timothy D. Howard, Richard S. Vander Heide, Jennifer Van Eyk, Yue Wang, David M. Herrington
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
Medicine
R
Science
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Online Access:https://doaj.org/article/485c84a505f64a21bc57f4bf322cab09
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https://doaj.org/article/485c84a505f64a21bc57f4bf322cab09

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