AAV-ie enables safe and efficient gene transfer to inner ear cells

There are currently few AAV vectors that can effectively target the diverse cell types of the inner ear. Here the authors design AAV-ie for gene delivery to the mouse cochlea, targeting cochlear supporting cells.

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Detalles Bibliográficos
Autores principales:	Fangzhi Tan, Cenfeng Chu, Jieyu Qi, Wenyan Li, Dan You, Ke Li, Xin Chen, Weidong Zhao, Cheng Cheng, Xiaoyi Liu, Yunbo Qiao, Bing Su, Shuijin He, Chao Zhong, Huawei Li, Renjie Chai, Guisheng Zhong
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/4870f102e8cb420483631d047f236268
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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spelling	oai:doaj.org-article:4870f102e8cb420483631d047f2362682021-12-02T14:38:37ZAAV-ie enables safe and efficient gene transfer to inner ear cells10.1038/s41467-019-11687-82041-1723https://doaj.org/article/4870f102e8cb420483631d047f2362682019-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11687-8https://doaj.org/toc/2041-1723There are currently few AAV vectors that can effectively target the diverse cell types of the inner ear. Here the authors design AAV-ie for gene delivery to the mouse cochlea, targeting cochlear supporting cells.Fangzhi TanCenfeng ChuJieyu QiWenyan LiDan YouKe LiXin ChenWeidong ZhaoCheng ChengXiaoyi LiuYunbo QiaoBing SuShuijin HeChao ZhongHuawei LiRenjie ChaiGuisheng ZhongNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Fangzhi Tan Cenfeng Chu Jieyu Qi Wenyan Li Dan You Ke Li Xin Chen Weidong Zhao Cheng Cheng Xiaoyi Liu Yunbo Qiao Bing Su Shuijin He Chao Zhong Huawei Li Renjie Chai Guisheng Zhong AAV-ie enables safe and efficient gene transfer to inner ear cells
description	There are currently few AAV vectors that can effectively target the diverse cell types of the inner ear. Here the authors design AAV-ie for gene delivery to the mouse cochlea, targeting cochlear supporting cells.
format	article
author	Fangzhi Tan Cenfeng Chu Jieyu Qi Wenyan Li Dan You Ke Li Xin Chen Weidong Zhao Cheng Cheng Xiaoyi Liu Yunbo Qiao Bing Su Shuijin He Chao Zhong Huawei Li Renjie Chai Guisheng Zhong
author_facet	Fangzhi Tan Cenfeng Chu Jieyu Qi Wenyan Li Dan You Ke Li Xin Chen Weidong Zhao Cheng Cheng Xiaoyi Liu Yunbo Qiao Bing Su Shuijin He Chao Zhong Huawei Li Renjie Chai Guisheng Zhong
author_sort	Fangzhi Tan
title	AAV-ie enables safe and efficient gene transfer to inner ear cells
title_short	AAV-ie enables safe and efficient gene transfer to inner ear cells
title_full	AAV-ie enables safe and efficient gene transfer to inner ear cells
title_fullStr	AAV-ie enables safe and efficient gene transfer to inner ear cells
title_full_unstemmed	AAV-ie enables safe and efficient gene transfer to inner ear cells
title_sort	aav-ie enables safe and efficient gene transfer to inner ear cells
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/4870f102e8cb420483631d047f236268
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AAV-ie enables safe and efficient gene transfer to inner ear cells

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