Metabolomic profiling in a Hedgehog Interacting Protein (Hhip) murine model of chronic obstructive pulmonary disease

Metabolomic profiling in a Hedgehog Interacting Protein (Hhip) murine model of chronic obstructive pulmonary disease

Abstract Genetic variants annotated to the hedgehog interacting protein (HHIP) are robustly associated with chronic obstructive pulmonary disease (COPD). Hhip haploinsufficiency in mice leads to increased susceptibility towards the development of emphysema following exposure to chronic cigarette smo...

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Autores principales: Emily S. Wan, Yan Li, Taotao Lao, Weiliang Qiu, Zhiqiang Jiang, John D. Mancini, Caroline A. Owen, Clary Clish, Dawn L. DeMeo, Edwin K. Silverman, Xiaobo Zhou
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/487ff678e8004996a3d6158b2118fde2
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