IGF-1 receptor regulates dynamic changes in neuronal polarity during cerebral cortical migration

IGF-1 receptor regulates dynamic changes in neuronal polarity during cerebral cortical migration

Abstract During cortical development, neurons undergo polarization, oriented migration and layer-type differentiation. The biological and biochemical mechanisms underlying these processes are not completely understood. In neurons in culture we showed that IGF-1 receptor activation is important for g...

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Autores principales: Alvaro F. Nieto Guil, Mariana Oksdath, Linnea A. Weiss, Diego J. Grassi, Lucas J. Sosa, Marta Nieto, Santiago Quiroga
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/4883c92662b045dda79d1eb15277e16a
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