Formalising recall by genotype as an efficient approach to detailed phenotyping and causal inference

Formalising recall by genotype as an efficient approach to detailed phenotyping and causal inference

Recall-by-Genotype (RbG) is an approach to recall participants from genetic studies based on their specific genotype for further, more extensive phenotyping. Here, the authors discuss examples of RbG as well as practical and ethical considerations and provide an online tool to aid in designing RbG s...

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Auteurs principaux: Laura J. Corbin, Vanessa Y. Tan, David A. Hughes, Kaitlin H. Wade, Dirk S. Paul, Katherine E. Tansey, Frances Butcher, Frank Dudbridge, Joanna M. Howson, Momodou W. Jallow, Catherine John, Nathalie Kingston, Cecilia M. Lindgren, Michael O’Donavan, Stephen O’Rahilly, Michael J. Owen, Colin N. A. Palmer, Ewan R. Pearson, Robert A. Scott, David A. van Heel, John Whittaker, Tim Frayling, Martin D. Tobin, Louise V. Wain, George Davey Smith, David M. Evans, Fredrik Karpe, Mark I. McCarthy, John Danesh, Paul W. Franks, Nicholas J. Timpson
Format: article
Langue:EN
Publié: Nature Portfolio 2018
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Science
Q
Accès en ligne:https://doaj.org/article/4889e7ce60af487a8fa26fd2a38318e8
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https://doaj.org/article/4889e7ce60af487a8fa26fd2a38318e8

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