Efficient rational modification of non-ribosomal peptides by adenylation domain substitution
Non-ribosomal peptide synthases are multimodular enzymes comprised of adenylation (A), condensation (C) and thiolation domains. Here, the authors show that non-ribosomal peptides can be generated solely by A domain substitutions, providing evidence that the postulated substrate specifying role of C-...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
Nature Portfolio
2020
|
| Subjects: | |
| Online Access: | https://doaj.org/article/48924e1b8e5f493994a0d6dff8b81874 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|