Capsaicin-induced activation of p53-SMAR1 auto-regulatory loop down-regulates VEGF in non-small cell lung cancer to restrain angiogenesis.

Capsaicin-induced activation of p53-SMAR1 auto-regulatory loop down-regulates VEGF in non-small cell lung cancer to restrain angiogenesis.

Lung cancer is the leading cause of cancer-related deaths worldwide. Despite decades of research, the treatment options for lung cancer patients remain inadequate, either to offer a cure or even a substantial survival advantage owing to its intrinsic resistance to chemotherapy. Our results propose t...

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Autores principales: Samik Chakraborty, Arghya Adhikary, Minakshi Mazumdar, Shravanti Mukherjee, Pushpak Bhattacharjee, Deblina Guha, Tathagata Choudhuri, Samit Chattopadhyay, Gaurisankar Sa, Aparna Sen, Tanya Das
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/48957223d22c4bd3bae714c655194b96
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