MicroRNA-92a is a circadian modulator of neuronal excitability in Drosophila

Accumulating evidence suggests that microRNAs play a role in circadian regulation. Here the authors show that in theDrosophila brain, mir-92a suppresses the excitability of PDF neurons—key circadian pacemaker cells in Drosophila—via inhibiting the translation of its target sirt2.

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Detalles Bibliográficos
Autores principales:	Xiao Chen, Michael Rosbash
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/489b58bf499f4508a9634b2675dbbd1d
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spelling	oai:doaj.org-article:489b58bf499f4508a9634b2675dbbd1d2021-12-02T14:42:26ZMicroRNA-92a is a circadian modulator of neuronal excitability in Drosophila10.1038/ncomms147072041-1723https://doaj.org/article/489b58bf499f4508a9634b2675dbbd1d2017-03-01T00:00:00Zhttps://doi.org/10.1038/ncomms14707https://doaj.org/toc/2041-1723Accumulating evidence suggests that microRNAs play a role in circadian regulation. Here the authors show that in theDrosophila brain, mir-92a suppresses the excitability of PDF neurons—key circadian pacemaker cells in Drosophila—via inhibiting the translation of its target sirt2.Xiao ChenMichael RosbashNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Xiao Chen Michael Rosbash MicroRNA-92a is a circadian modulator of neuronal excitability in Drosophila
description	Accumulating evidence suggests that microRNAs play a role in circadian regulation. Here the authors show that in theDrosophila brain, mir-92a suppresses the excitability of PDF neurons—key circadian pacemaker cells in Drosophila—via inhibiting the translation of its target sirt2.
format	article
author	Xiao Chen Michael Rosbash
author_facet	Xiao Chen Michael Rosbash
author_sort	Xiao Chen
title	MicroRNA-92a is a circadian modulator of neuronal excitability in Drosophila
title_short	MicroRNA-92a is a circadian modulator of neuronal excitability in Drosophila
title_full	MicroRNA-92a is a circadian modulator of neuronal excitability in Drosophila
title_fullStr	MicroRNA-92a is a circadian modulator of neuronal excitability in Drosophila
title_full_unstemmed	MicroRNA-92a is a circadian modulator of neuronal excitability in Drosophila
title_sort	microrna-92a is a circadian modulator of neuronal excitability in drosophila
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/489b58bf499f4508a9634b2675dbbd1d
work_keys_str_mv	AT xiaochen microrna92aisacircadianmodulatorofneuronalexcitabilityindrosophila AT michaelrosbash microrna92aisacircadianmodulatorofneuronalexcitabilityindrosophila
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MicroRNA-92a is a circadian modulator of neuronal excitability in Drosophila

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