Electrochemically synthesized highly crystalline nitrogen doped graphene nanosheets with exceptional biocompatibility

Abstract This work reports first electrochemical preparation of exceptionally biocompatible, highly crystalline, and well exfoliated nitrogen doped graphene nanosheets (eNGS) from carbon nanosheets for the development of mighty platforms in the field of modern biosensing and other biological applica...

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Autores principales:	Deepa Suhag, Arun Kumar Sharma, Satyendra K. Rajput, Gajender Saini, Sandip Chakrabarti, Monalisa Mukherjee
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/489ef606014841538eb96ab9465beea0
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spelling	oai:doaj.org-article:489ef606014841538eb96ab9465beea02021-12-02T16:06:34ZElectrochemically synthesized highly crystalline nitrogen doped graphene nanosheets with exceptional biocompatibility10.1038/s41598-017-00616-82045-2322https://doaj.org/article/489ef606014841538eb96ab9465beea02017-04-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-00616-8https://doaj.org/toc/2045-2322Abstract This work reports first electrochemical preparation of exceptionally biocompatible, highly crystalline, and well exfoliated nitrogen doped graphene nanosheets (eNGS) from carbon nanosheets for the development of mighty platforms in the field of modern biosensing and other biological applications for human welfare. eNGS displayed exceptional biocompatibility. Administration of the as-synthesized eNGS to rat models did not lead to any significant deviation or inimical consequences in its functional observation battery (FOB) tests, GSH levels or the histology of the vital organs of the rat models. The pictomicrographs of myocytes nuclei and myofibrillar for heart, hippocampus (CA1) section for brain, central vein, and hepatocytes for liver and parenchyma, tubules and glomeruli for kidney also remained unaffected. Moreover, the resultant nanoelectrocatalyst displayed enhanced electrochemical performance towards real-time sensing of dopamine (DA) from human urine sample in the presence of interferences, such as ascorbic acid (AA) and uric acid (UA).Deepa SuhagArun Kumar SharmaSatyendra K. RajputGajender SainiSandip ChakrabartiMonalisa MukherjeeNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Deepa Suhag Arun Kumar Sharma Satyendra K. Rajput Gajender Saini Sandip Chakrabarti Monalisa Mukherjee Electrochemically synthesized highly crystalline nitrogen doped graphene nanosheets with exceptional biocompatibility
description	Abstract This work reports first electrochemical preparation of exceptionally biocompatible, highly crystalline, and well exfoliated nitrogen doped graphene nanosheets (eNGS) from carbon nanosheets for the development of mighty platforms in the field of modern biosensing and other biological applications for human welfare. eNGS displayed exceptional biocompatibility. Administration of the as-synthesized eNGS to rat models did not lead to any significant deviation or inimical consequences in its functional observation battery (FOB) tests, GSH levels or the histology of the vital organs of the rat models. The pictomicrographs of myocytes nuclei and myofibrillar for heart, hippocampus (CA1) section for brain, central vein, and hepatocytes for liver and parenchyma, tubules and glomeruli for kidney also remained unaffected. Moreover, the resultant nanoelectrocatalyst displayed enhanced electrochemical performance towards real-time sensing of dopamine (DA) from human urine sample in the presence of interferences, such as ascorbic acid (AA) and uric acid (UA).
format	article
author	Deepa Suhag Arun Kumar Sharma Satyendra K. Rajput Gajender Saini Sandip Chakrabarti Monalisa Mukherjee
author_facet	Deepa Suhag Arun Kumar Sharma Satyendra K. Rajput Gajender Saini Sandip Chakrabarti Monalisa Mukherjee
author_sort	Deepa Suhag
title	Electrochemically synthesized highly crystalline nitrogen doped graphene nanosheets with exceptional biocompatibility
title_short	Electrochemically synthesized highly crystalline nitrogen doped graphene nanosheets with exceptional biocompatibility
title_full	Electrochemically synthesized highly crystalline nitrogen doped graphene nanosheets with exceptional biocompatibility
title_fullStr	Electrochemically synthesized highly crystalline nitrogen doped graphene nanosheets with exceptional biocompatibility
title_full_unstemmed	Electrochemically synthesized highly crystalline nitrogen doped graphene nanosheets with exceptional biocompatibility
title_sort	electrochemically synthesized highly crystalline nitrogen doped graphene nanosheets with exceptional biocompatibility
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/489ef606014841538eb96ab9465beea0
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Electrochemically synthesized highly crystalline nitrogen doped graphene nanosheets with exceptional biocompatibility

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