Sensory cortex wiring requires preselection of short- and long-range projection neurons through an Egr-Foxg1-COUP-TFI network

Layer 4 spiny stellate cells project locally while pyramidal neurons have long-range projections yet the molecular program that determines their specificity is not yet known. Here, the authors demonstrate that Egr, Foxg1 and COUP-TFI transcription factors play causal role in the specification of the...

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Autores principales:	Pei-Shan Hou, Goichi Miyoshi, Carina Hanashima
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/48b0de6421fd4995891426dc7e545cac
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id	oai:doaj.org-article:48b0de6421fd4995891426dc7e545cac
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spelling	oai:doaj.org-article:48b0de6421fd4995891426dc7e545cac2021-12-02T16:58:25ZSensory cortex wiring requires preselection of short- and long-range projection neurons through an Egr-Foxg1-COUP-TFI network10.1038/s41467-019-11043-w2041-1723https://doaj.org/article/48b0de6421fd4995891426dc7e545cac2019-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11043-whttps://doaj.org/toc/2041-1723Layer 4 spiny stellate cells project locally while pyramidal neurons have long-range projections yet the molecular program that determines their specificity is not yet known. Here, the authors demonstrate that Egr, Foxg1 and COUP-TFI transcription factors play causal role in the specification of these cell types.Pei-Shan HouGoichi MiyoshiCarina HanashimaNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-18 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Pei-Shan Hou Goichi Miyoshi Carina Hanashima Sensory cortex wiring requires preselection of short- and long-range projection neurons through an Egr-Foxg1-COUP-TFI network
description	Layer 4 spiny stellate cells project locally while pyramidal neurons have long-range projections yet the molecular program that determines their specificity is not yet known. Here, the authors demonstrate that Egr, Foxg1 and COUP-TFI transcription factors play causal role in the specification of these cell types.
format	article
author	Pei-Shan Hou Goichi Miyoshi Carina Hanashima
author_facet	Pei-Shan Hou Goichi Miyoshi Carina Hanashima
author_sort	Pei-Shan Hou
title	Sensory cortex wiring requires preselection of short- and long-range projection neurons through an Egr-Foxg1-COUP-TFI network
title_short	Sensory cortex wiring requires preselection of short- and long-range projection neurons through an Egr-Foxg1-COUP-TFI network
title_full	Sensory cortex wiring requires preselection of short- and long-range projection neurons through an Egr-Foxg1-COUP-TFI network
title_fullStr	Sensory cortex wiring requires preselection of short- and long-range projection neurons through an Egr-Foxg1-COUP-TFI network
title_full_unstemmed	Sensory cortex wiring requires preselection of short- and long-range projection neurons through an Egr-Foxg1-COUP-TFI network
title_sort	sensory cortex wiring requires preselection of short- and long-range projection neurons through an egr-foxg1-coup-tfi network
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/48b0de6421fd4995891426dc7e545cac
work_keys_str_mv	AT peishanhou sensorycortexwiringrequirespreselectionofshortandlongrangeprojectionneuronsthroughanegrfoxg1couptfinetwork AT goichimiyoshi sensorycortexwiringrequirespreselectionofshortandlongrangeprojectionneuronsthroughanegrfoxg1couptfinetwork AT carinahanashima sensorycortexwiringrequirespreselectionofshortandlongrangeprojectionneuronsthroughanegrfoxg1couptfinetwork
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Sensory cortex wiring requires preselection of short- and long-range projection neurons through an Egr-Foxg1-COUP-TFI network

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