Chitin-based barrier immunity and its loss predated mucus-colonization by indigenous gut microbiota

The coevolution of the animal gut mucosa and the gut microbiota is poorly understood. Here, Nakashima et al. identify intestinal chitinous membranes in basal chordates and ray-finned fish, and propose that the loss of this chitin barrier allowed mucus layers to become colonized by microbes in mammal...

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Autores principales:	Keisuke Nakashima, Satoshi Kimura, Yu Ogawa, Soichi Watanabe, Satoshi Soma, Toyoji Kaneko, Lixy Yamada, Hitoshi Sawada, Che-Huang Tung, Tsai-Ming Lu, Jr-Kai Yu, Alejandro Villar-Briones, Sakura Kikuchi, Noriyuki Satoh
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/48b3204bc18a4060ae3215c178930765
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spelling	oai:doaj.org-article:48b3204bc18a4060ae3215c1789307652021-12-02T17:32:18ZChitin-based barrier immunity and its loss predated mucus-colonization by indigenous gut microbiota10.1038/s41467-018-05884-02041-1723https://doaj.org/article/48b3204bc18a4060ae3215c1789307652018-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05884-0https://doaj.org/toc/2041-1723The coevolution of the animal gut mucosa and the gut microbiota is poorly understood. Here, Nakashima et al. identify intestinal chitinous membranes in basal chordates and ray-finned fish, and propose that the loss of this chitin barrier allowed mucus layers to become colonized by microbes in mammals.Keisuke NakashimaSatoshi KimuraYu OgawaSoichi WatanabeSatoshi SomaToyoji KanekoLixy YamadaHitoshi SawadaChe-Huang TungTsai-Ming LuJr-Kai YuAlejandro Villar-BrionesSakura KikuchiNoriyuki SatohNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Keisuke Nakashima Satoshi Kimura Yu Ogawa Soichi Watanabe Satoshi Soma Toyoji Kaneko Lixy Yamada Hitoshi Sawada Che-Huang Tung Tsai-Ming Lu Jr-Kai Yu Alejandro Villar-Briones Sakura Kikuchi Noriyuki Satoh Chitin-based barrier immunity and its loss predated mucus-colonization by indigenous gut microbiota
description	The coevolution of the animal gut mucosa and the gut microbiota is poorly understood. Here, Nakashima et al. identify intestinal chitinous membranes in basal chordates and ray-finned fish, and propose that the loss of this chitin barrier allowed mucus layers to become colonized by microbes in mammals.
format	article
author	Keisuke Nakashima Satoshi Kimura Yu Ogawa Soichi Watanabe Satoshi Soma Toyoji Kaneko Lixy Yamada Hitoshi Sawada Che-Huang Tung Tsai-Ming Lu Jr-Kai Yu Alejandro Villar-Briones Sakura Kikuchi Noriyuki Satoh
author_facet	Keisuke Nakashima Satoshi Kimura Yu Ogawa Soichi Watanabe Satoshi Soma Toyoji Kaneko Lixy Yamada Hitoshi Sawada Che-Huang Tung Tsai-Ming Lu Jr-Kai Yu Alejandro Villar-Briones Sakura Kikuchi Noriyuki Satoh
author_sort	Keisuke Nakashima
title	Chitin-based barrier immunity and its loss predated mucus-colonization by indigenous gut microbiota
title_short	Chitin-based barrier immunity and its loss predated mucus-colonization by indigenous gut microbiota
title_full	Chitin-based barrier immunity and its loss predated mucus-colonization by indigenous gut microbiota
title_fullStr	Chitin-based barrier immunity and its loss predated mucus-colonization by indigenous gut microbiota
title_full_unstemmed	Chitin-based barrier immunity and its loss predated mucus-colonization by indigenous gut microbiota
title_sort	chitin-based barrier immunity and its loss predated mucus-colonization by indigenous gut microbiota
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/48b3204bc18a4060ae3215c178930765
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Chitin-based barrier immunity and its loss predated mucus-colonization by indigenous gut microbiota

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