Plant-made polio type 3 stabilized VLPs—a candidate synthetic polio vaccine
Despite the success of current vaccination against poliomyelitis, safe, cheap and effective vaccines remain sought for continuing eradication effort. Here the authors use plants to express stabilized virus-like particles of type 3 poliovirus that can induce a protective immune response in mice trans...
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Nature Portfolio
2017
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oai:doaj.org-article:48bce09b6ee24f948fdf9a32e9d5ba0a2021-12-02T13:24:33ZPlant-made polio type 3 stabilized VLPs—a candidate synthetic polio vaccine10.1038/s41467-017-00090-w2041-1723https://doaj.org/article/48bce09b6ee24f948fdf9a32e9d5ba0a2017-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00090-whttps://doaj.org/toc/2041-1723Despite the success of current vaccination against poliomyelitis, safe, cheap and effective vaccines remain sought for continuing eradication effort. Here the authors use plants to express stabilized virus-like particles of type 3 poliovirus that can induce a protective immune response in mice transgenic for the human poliovirus receptor.Johanna MarsianHelen FoxMohammad W. BaharAbhay KotechaElizabeth E. FryDavid I. StuartAndrew J. MacadamDavid J. RowlandsGeorge P. LomonossoffNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-9 (2017) |
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Science Q Johanna Marsian Helen Fox Mohammad W. Bahar Abhay Kotecha Elizabeth E. Fry David I. Stuart Andrew J. Macadam David J. Rowlands George P. Lomonossoff Plant-made polio type 3 stabilized VLPs—a candidate synthetic polio vaccine |
description |
Despite the success of current vaccination against poliomyelitis, safe, cheap and effective vaccines remain sought for continuing eradication effort. Here the authors use plants to express stabilized virus-like particles of type 3 poliovirus that can induce a protective immune response in mice transgenic for the human poliovirus receptor. |
format |
article |
author |
Johanna Marsian Helen Fox Mohammad W. Bahar Abhay Kotecha Elizabeth E. Fry David I. Stuart Andrew J. Macadam David J. Rowlands George P. Lomonossoff |
author_facet |
Johanna Marsian Helen Fox Mohammad W. Bahar Abhay Kotecha Elizabeth E. Fry David I. Stuart Andrew J. Macadam David J. Rowlands George P. Lomonossoff |
author_sort |
Johanna Marsian |
title |
Plant-made polio type 3 stabilized VLPs—a candidate synthetic polio vaccine |
title_short |
Plant-made polio type 3 stabilized VLPs—a candidate synthetic polio vaccine |
title_full |
Plant-made polio type 3 stabilized VLPs—a candidate synthetic polio vaccine |
title_fullStr |
Plant-made polio type 3 stabilized VLPs—a candidate synthetic polio vaccine |
title_full_unstemmed |
Plant-made polio type 3 stabilized VLPs—a candidate synthetic polio vaccine |
title_sort |
plant-made polio type 3 stabilized vlps—a candidate synthetic polio vaccine |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/48bce09b6ee24f948fdf9a32e9d5ba0a |
work_keys_str_mv |
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1718393091758489600 |