Plant-made polio type 3 stabilized VLPs—a candidate synthetic polio vaccine

Despite the success of current vaccination against poliomyelitis, safe, cheap and effective vaccines remain sought for continuing eradication effort. Here the authors use plants to express stabilized virus-like particles of type 3 poliovirus that can induce a protective immune response in mice trans...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Johanna Marsian, Helen Fox, Mohammad W. Bahar, Abhay Kotecha, Elizabeth E. Fry, David I. Stuart, Andrew J. Macadam, David J. Rowlands, George P. Lomonossoff
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Q
Acceso en línea:https://doaj.org/article/48bce09b6ee24f948fdf9a32e9d5ba0a
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:48bce09b6ee24f948fdf9a32e9d5ba0a
record_format dspace
spelling oai:doaj.org-article:48bce09b6ee24f948fdf9a32e9d5ba0a2021-12-02T13:24:33ZPlant-made polio type 3 stabilized VLPs—a candidate synthetic polio vaccine10.1038/s41467-017-00090-w2041-1723https://doaj.org/article/48bce09b6ee24f948fdf9a32e9d5ba0a2017-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00090-whttps://doaj.org/toc/2041-1723Despite the success of current vaccination against poliomyelitis, safe, cheap and effective vaccines remain sought for continuing eradication effort. Here the authors use plants to express stabilized virus-like particles of type 3 poliovirus that can induce a protective immune response in mice transgenic for the human poliovirus receptor.Johanna MarsianHelen FoxMohammad W. BaharAbhay KotechaElizabeth E. FryDavid I. StuartAndrew J. MacadamDavid J. RowlandsGeorge P. LomonossoffNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Johanna Marsian
Helen Fox
Mohammad W. Bahar
Abhay Kotecha
Elizabeth E. Fry
David I. Stuart
Andrew J. Macadam
David J. Rowlands
George P. Lomonossoff
Plant-made polio type 3 stabilized VLPs—a candidate synthetic polio vaccine
description Despite the success of current vaccination against poliomyelitis, safe, cheap and effective vaccines remain sought for continuing eradication effort. Here the authors use plants to express stabilized virus-like particles of type 3 poliovirus that can induce a protective immune response in mice transgenic for the human poliovirus receptor.
format article
author Johanna Marsian
Helen Fox
Mohammad W. Bahar
Abhay Kotecha
Elizabeth E. Fry
David I. Stuart
Andrew J. Macadam
David J. Rowlands
George P. Lomonossoff
author_facet Johanna Marsian
Helen Fox
Mohammad W. Bahar
Abhay Kotecha
Elizabeth E. Fry
David I. Stuart
Andrew J. Macadam
David J. Rowlands
George P. Lomonossoff
author_sort Johanna Marsian
title Plant-made polio type 3 stabilized VLPs—a candidate synthetic polio vaccine
title_short Plant-made polio type 3 stabilized VLPs—a candidate synthetic polio vaccine
title_full Plant-made polio type 3 stabilized VLPs—a candidate synthetic polio vaccine
title_fullStr Plant-made polio type 3 stabilized VLPs—a candidate synthetic polio vaccine
title_full_unstemmed Plant-made polio type 3 stabilized VLPs—a candidate synthetic polio vaccine
title_sort plant-made polio type 3 stabilized vlps—a candidate synthetic polio vaccine
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/48bce09b6ee24f948fdf9a32e9d5ba0a
work_keys_str_mv AT johannamarsian plantmadepoliotype3stabilizedvlpsacandidatesyntheticpoliovaccine
AT helenfox plantmadepoliotype3stabilizedvlpsacandidatesyntheticpoliovaccine
AT mohammadwbahar plantmadepoliotype3stabilizedvlpsacandidatesyntheticpoliovaccine
AT abhaykotecha plantmadepoliotype3stabilizedvlpsacandidatesyntheticpoliovaccine
AT elizabethefry plantmadepoliotype3stabilizedvlpsacandidatesyntheticpoliovaccine
AT davidistuart plantmadepoliotype3stabilizedvlpsacandidatesyntheticpoliovaccine
AT andrewjmacadam plantmadepoliotype3stabilizedvlpsacandidatesyntheticpoliovaccine
AT davidjrowlands plantmadepoliotype3stabilizedvlpsacandidatesyntheticpoliovaccine
AT georgeplomonossoff plantmadepoliotype3stabilizedvlpsacandidatesyntheticpoliovaccine
_version_ 1718393091758489600