Engineered immunological niches to monitor disease activity and treatment efficacy in relapsing multiple sclerosis

Monitoring changes in immune phenotype during the progression of multiple sclerosis can provide insight into disease progression and inform treatment. Here the authors develop engineered biomaterial-based immunological niches for easy access to innate immune cells in a mouse model of multiple sclero...

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Autores principales:	Aaron H. Morris, Kevin R. Hughes, Robert S. Oakes, Michelle M. Cai, Stephen D. Miller, David N. Irani, Lonnie D. Shea
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/48cb7a477ac048fcac336e5030785778
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spelling	oai:doaj.org-article:48cb7a477ac048fcac336e50307857782021-12-02T16:36:37ZEngineered immunological niches to monitor disease activity and treatment efficacy in relapsing multiple sclerosis10.1038/s41467-020-17629-z2041-1723https://doaj.org/article/48cb7a477ac048fcac336e50307857782020-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17629-zhttps://doaj.org/toc/2041-1723Monitoring changes in immune phenotype during the progression of multiple sclerosis can provide insight into disease progression and inform treatment. Here the authors develop engineered biomaterial-based immunological niches for easy access to innate immune cells in a mouse model of multiple sclerosis.Aaron H. MorrisKevin R. HughesRobert S. OakesMichelle M. CaiStephen D. MillerDavid N. IraniLonnie D. SheaNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Aaron H. Morris Kevin R. Hughes Robert S. Oakes Michelle M. Cai Stephen D. Miller David N. Irani Lonnie D. Shea Engineered immunological niches to monitor disease activity and treatment efficacy in relapsing multiple sclerosis
description	Monitoring changes in immune phenotype during the progression of multiple sclerosis can provide insight into disease progression and inform treatment. Here the authors develop engineered biomaterial-based immunological niches for easy access to innate immune cells in a mouse model of multiple sclerosis.
format	article
author	Aaron H. Morris Kevin R. Hughes Robert S. Oakes Michelle M. Cai Stephen D. Miller David N. Irani Lonnie D. Shea
author_facet	Aaron H. Morris Kevin R. Hughes Robert S. Oakes Michelle M. Cai Stephen D. Miller David N. Irani Lonnie D. Shea
author_sort	Aaron H. Morris
title	Engineered immunological niches to monitor disease activity and treatment efficacy in relapsing multiple sclerosis
title_short	Engineered immunological niches to monitor disease activity and treatment efficacy in relapsing multiple sclerosis
title_full	Engineered immunological niches to monitor disease activity and treatment efficacy in relapsing multiple sclerosis
title_fullStr	Engineered immunological niches to monitor disease activity and treatment efficacy in relapsing multiple sclerosis
title_full_unstemmed	Engineered immunological niches to monitor disease activity and treatment efficacy in relapsing multiple sclerosis
title_sort	engineered immunological niches to monitor disease activity and treatment efficacy in relapsing multiple sclerosis
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/48cb7a477ac048fcac336e5030785778
work_keys_str_mv	AT aaronhmorris engineeredimmunologicalnichestomonitordiseaseactivityandtreatmentefficacyinrelapsingmultiplesclerosis AT kevinrhughes engineeredimmunologicalnichestomonitordiseaseactivityandtreatmentefficacyinrelapsingmultiplesclerosis AT robertsoakes engineeredimmunologicalnichestomonitordiseaseactivityandtreatmentefficacyinrelapsingmultiplesclerosis AT michellemcai engineeredimmunologicalnichestomonitordiseaseactivityandtreatmentefficacyinrelapsingmultiplesclerosis AT stephendmiller engineeredimmunologicalnichestomonitordiseaseactivityandtreatmentefficacyinrelapsingmultiplesclerosis AT davidnirani engineeredimmunologicalnichestomonitordiseaseactivityandtreatmentefficacyinrelapsingmultiplesclerosis AT lonniedshea engineeredimmunologicalnichestomonitordiseaseactivityandtreatmentefficacyinrelapsingmultiplesclerosis
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Engineered immunological niches to monitor disease activity and treatment efficacy in relapsing multiple sclerosis

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