Secretory phospholipase A2 modified HDL rapidly and potently suppresses platelet activation

Secretory phospholipase A2 modified HDL rapidly and potently suppresses platelet activation

Abstract Levels of secretory phospholipases A2 (sPLA2) highly increase under acute and chronic inflammatory conditions. sPLA2 is mainly associated with high-density lipoproteins (HDL) and generates bioactive lysophospholipids implicated in acute and chronic inflammatory processes. Unexpectedly, phar...

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Autores principales: Sanja Curcic, Michael Holzer, Lisa Pasterk, Eva Knuplez, Thomas O. Eichmann, Saša Frank, Robert Zimmermann, Rudolf Schicho, Akos Heinemann, Gunther Marsche
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
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Acceso en línea:https://doaj.org/article/48d7c4c6f75c4565921dcb6695e9d898
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