Longitudinal analysis of blood markers reveals progressive loss of resilience and predicts human lifespan limit

Aging is associated with an increased risk of chronic diseases and functional decline. Here, the authors investigate the fluctuations of physiological indices along aging trajectories and observed a characteristic decrease in the organism state recovery rate.

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Autores principales:	Timothy V. Pyrkov, Konstantin Avchaciov, Andrei E. Tarkhov, Leonid I. Menshikov, Andrei V. Gudkov, Peter O. Fedichev
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/48de15a8f1014ada8274110622c45562
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spelling	oai:doaj.org-article:48de15a8f1014ada8274110622c455622021-12-02T16:53:16ZLongitudinal analysis of blood markers reveals progressive loss of resilience and predicts human lifespan limit10.1038/s41467-021-23014-12041-1723https://doaj.org/article/48de15a8f1014ada8274110622c455622021-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-23014-1https://doaj.org/toc/2041-1723Aging is associated with an increased risk of chronic diseases and functional decline. Here, the authors investigate the fluctuations of physiological indices along aging trajectories and observed a characteristic decrease in the organism state recovery rate.Timothy V. PyrkovKonstantin AvchaciovAndrei E. TarkhovLeonid I. MenshikovAndrei V. GudkovPeter O. FedichevNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Timothy V. Pyrkov Konstantin Avchaciov Andrei E. Tarkhov Leonid I. Menshikov Andrei V. Gudkov Peter O. Fedichev Longitudinal analysis of blood markers reveals progressive loss of resilience and predicts human lifespan limit
description	Aging is associated with an increased risk of chronic diseases and functional decline. Here, the authors investigate the fluctuations of physiological indices along aging trajectories and observed a characteristic decrease in the organism state recovery rate.
format	article
author	Timothy V. Pyrkov Konstantin Avchaciov Andrei E. Tarkhov Leonid I. Menshikov Andrei V. Gudkov Peter O. Fedichev
author_facet	Timothy V. Pyrkov Konstantin Avchaciov Andrei E. Tarkhov Leonid I. Menshikov Andrei V. Gudkov Peter O. Fedichev
author_sort	Timothy V. Pyrkov
title	Longitudinal analysis of blood markers reveals progressive loss of resilience and predicts human lifespan limit
title_short	Longitudinal analysis of blood markers reveals progressive loss of resilience and predicts human lifespan limit
title_full	Longitudinal analysis of blood markers reveals progressive loss of resilience and predicts human lifespan limit
title_fullStr	Longitudinal analysis of blood markers reveals progressive loss of resilience and predicts human lifespan limit
title_full_unstemmed	Longitudinal analysis of blood markers reveals progressive loss of resilience and predicts human lifespan limit
title_sort	longitudinal analysis of blood markers reveals progressive loss of resilience and predicts human lifespan limit
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/48de15a8f1014ada8274110622c45562
work_keys_str_mv	AT timothyvpyrkov longitudinalanalysisofbloodmarkersrevealsprogressivelossofresilienceandpredictshumanlifespanlimit AT konstantinavchaciov longitudinalanalysisofbloodmarkersrevealsprogressivelossofresilienceandpredictshumanlifespanlimit AT andreietarkhov longitudinalanalysisofbloodmarkersrevealsprogressivelossofresilienceandpredictshumanlifespanlimit AT leonidimenshikov longitudinalanalysisofbloodmarkersrevealsprogressivelossofresilienceandpredictshumanlifespanlimit AT andreivgudkov longitudinalanalysisofbloodmarkersrevealsprogressivelossofresilienceandpredictshumanlifespanlimit AT peterofedichev longitudinalanalysisofbloodmarkersrevealsprogressivelossofresilienceandpredictshumanlifespanlimit
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Longitudinal analysis of blood markers reveals progressive loss of resilience and predicts human lifespan limit

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