Sprouty2 and Spred1-2 proteins inhibit the activation of the ERK pathway elicited by cyclopentenone prostanoids.

Sprouty and Spred proteins have been widely implicated in the negative regulation of the fibroblast growth factor receptor-extracellular regulated kinase (ERK) pathway. In considering the functional role of these proteins, we explored their effects on ERK activation induced by cyclopentenone prostan...

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Autores principales: Carlota A García-Domínguez, Natalia Martínez, Teresa Gragera, Andrea Pérez-Rodríguez, Diana Retana, Gonzalo León, Agustín Sánchez, José Luis Oliva, Dolores Pérez-Sala, José M Rojas
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
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Acceso en línea:https://doaj.org/article/48e19c28ab1c458eae1f03da80e9dcd9
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