Minimally invasive (MIE) vs open surgery for cancer of esophagus and GE junction. Long term results

Introduction: MIE is becoming a preferred approach for cancer of esophagus and GE junction, but its benefits have yet to be confirmed in randomized controlled trials. We performed a retrospective comparison between these two approaches for complications and survival results. Methods: Patients prim...

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Autores principales:	Binay Thakur, Di Yonghui, Mukti Devkota, Paribartan Baral, Yogesh Regmi, Rajendra Malli, Upsana Tiwari
Formato:	article
Lenguaje:	EN
Publicado:	Society of Surgeons of Nepal 2016
Materias:	Esophageal cancer Mckeon’s esophagectomy VATS Surgery RD1-811
Acceso en línea:	https://doaj.org/article/48e536ea978d459ebdecb43314016771
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spelling	oai:doaj.org-article:48e536ea978d459ebdecb433140167712021-12-05T19:16:45ZMinimally invasive (MIE) vs open surgery for cancer of esophagus and GE junction. Long term results10.3126/jssn.v18i3.152671815-39842392-4772https://doaj.org/article/48e536ea978d459ebdecb433140167712016-07-01T00:00:00Zhttps://www.nepjol.info/index.php/JSSN/article/view/15267https://doaj.org/toc/1815-3984https://doaj.org/toc/2392-4772 Introduction: MIE is becoming a preferred approach for cancer of esophagus and GE junction, but its benefits have yet to be confirmed in randomized controlled trials. We performed a retrospective comparison between these two approaches for complications and survival results. Methods: Patients primarily going for surgery or after neoadjuvant chemo/ chemoradiation were reviewed. MIE varied from totally thoracoscopic and laparoscopic to a hybrid approach. Both MIE and Open approaches were a three, two or one incision procedures. Results: MIE and open surgery were done in 128 and 293 patients, respectively. The mean basic parameters (referred as MIE/ Open) – age (59/ 57 years), duration of dysphagia (4/ 4 months), weight loss (8/ 9 kg), postoperative stay (13/ 14 days), hospital mortality (3/ 17), anastomotic leak (17/ 32), hoarseness of voice (8/ 16), number of harvested nodes (21/ 22), and R0 resection (122/ 263) did not differ significantly (p = ns). Mean operative time (265/ 240 mins) and intraoperative blood loss (325/ 436 ml) differed significantly (p < 0.05). Postoperative pneumonia was significantly less in MIE group (p<0.001). Median and 5-year overall survival was 33 months and 21% in MIE group; and 27 months and 20% in open group (p = 0.2) Conclusion: MIE and Open surgery did not differ in major postoperative complications except postoperative pneumonia, which was less in MIE. Both the procedures were similar in achieving R0 resection, median and 5-year overall survival. Binay ThakurDi YonghuiMukti DevkotaParibartan BaralYogesh RegmiRajendra MalliUpsana TiwariSociety of Surgeons of NepalarticleEsophageal cancerMckeon’s esophagectomyVATSSurgeryRD1-811ENJournal of Society of Surgeons of Nepal, Vol 18, Iss 3 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Esophageal cancer Mckeon’s esophagectomy VATS Surgery RD1-811
spellingShingle	Esophageal cancer Mckeon’s esophagectomy VATS Surgery RD1-811 Binay Thakur Di Yonghui Mukti Devkota Paribartan Baral Yogesh Regmi Rajendra Malli Upsana Tiwari Minimally invasive (MIE) vs open surgery for cancer of esophagus and GE junction. Long term results
description	Introduction: MIE is becoming a preferred approach for cancer of esophagus and GE junction, but its benefits have yet to be confirmed in randomized controlled trials. We performed a retrospective comparison between these two approaches for complications and survival results. Methods: Patients primarily going for surgery or after neoadjuvant chemo/ chemoradiation were reviewed. MIE varied from totally thoracoscopic and laparoscopic to a hybrid approach. Both MIE and Open approaches were a three, two or one incision procedures. Results: MIE and open surgery were done in 128 and 293 patients, respectively. The mean basic parameters (referred as MIE/ Open) – age (59/ 57 years), duration of dysphagia (4/ 4 months), weight loss (8/ 9 kg), postoperative stay (13/ 14 days), hospital mortality (3/ 17), anastomotic leak (17/ 32), hoarseness of voice (8/ 16), number of harvested nodes (21/ 22), and R0 resection (122/ 263) did not differ significantly (p = ns). Mean operative time (265/ 240 mins) and intraoperative blood loss (325/ 436 ml) differed significantly (p < 0.05). Postoperative pneumonia was significantly less in MIE group (p<0.001). Median and 5-year overall survival was 33 months and 21% in MIE group; and 27 months and 20% in open group (p = 0.2) Conclusion: MIE and Open surgery did not differ in major postoperative complications except postoperative pneumonia, which was less in MIE. Both the procedures were similar in achieving R0 resection, median and 5-year overall survival.
format	article
author	Binay Thakur Di Yonghui Mukti Devkota Paribartan Baral Yogesh Regmi Rajendra Malli Upsana Tiwari
author_facet	Binay Thakur Di Yonghui Mukti Devkota Paribartan Baral Yogesh Regmi Rajendra Malli Upsana Tiwari
author_sort	Binay Thakur
title	Minimally invasive (MIE) vs open surgery for cancer of esophagus and GE junction. Long term results
title_short	Minimally invasive (MIE) vs open surgery for cancer of esophagus and GE junction. Long term results
title_full	Minimally invasive (MIE) vs open surgery for cancer of esophagus and GE junction. Long term results
title_fullStr	Minimally invasive (MIE) vs open surgery for cancer of esophagus and GE junction. Long term results
title_full_unstemmed	Minimally invasive (MIE) vs open surgery for cancer of esophagus and GE junction. Long term results
title_sort	minimally invasive (mie) vs open surgery for cancer of esophagus and ge junction. long term results
publisher	Society of Surgeons of Nepal
publishDate	2016
url	https://doaj.org/article/48e536ea978d459ebdecb43314016771
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Minimally invasive (MIE) vs open surgery for cancer of esophagus and GE junction. Long term results

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