An unusual splice defect in the mitofusin 2 gene (MFN2) is associated with degenerative axonopathy in Tyrolean Grey cattle.

An unusual splice defect in the mitofusin 2 gene (MFN2) is associated with degenerative axonopathy in Tyrolean Grey cattle.

Tyrolean Grey cattle represent a local breed with a population size of ∼5000 registered cows. In 2003, a previously unknown neurological disorder was recognized in Tyrolean Grey cattle. The clinical signs of the disorder are similar to those of bovine progressive degenerative myeloencephalopathy (we...

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Autores principales: Cord Drögemüller, Ursula Reichart, Torsten Seuberlich, Anna Oevermann, Martin Baumgartner, Kathrin Kühni Boghenbor, Michael H Stoffel, Claudia Syring, Mireille Meylan, Simone Müller, Mathias Müller, Birgit Gredler, Johann Sölkner, Tosso Leeb
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
Materias:
Medicine
R
Science
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Acceso en línea:https://doaj.org/article/48e606e79f2147b8ba9b1a489fac075e
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