Cell-free protein synthesis from genomically recoded bacteria enables multisite incorporation of noncanonical amino acids

Cell-free protein synthesis allows for producing proteins without the need of a host organism, thus sparing the researcher experimental hassle. Here, the authors developed a cell-free synthesis method that enables incorporating non-standard amino acids in the product.

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Autores principales: Rey W. Martin, Benjamin J. Des Soye, Yong-Chan Kwon, Jennifer Kay, Roderick G. Davis, Paul M. Thomas, Natalia I. Majewska, Cindy X. Chen, Ryan D. Marcum, Mary Grace Weiss, Ashleigh E. Stoddart, Miriam Amiram, Arnaz K. Ranji Charna, Jaymin R. Patel, Farren J. Isaacs, Neil L. Kelleher, Seok Hoon Hong, Michael C. Jewett
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Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/48f02766cbcf45fab8fa2795bb729a58
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spelling oai:doaj.org-article:48f02766cbcf45fab8fa2795bb729a582021-12-02T14:40:30ZCell-free protein synthesis from genomically recoded bacteria enables multisite incorporation of noncanonical amino acids10.1038/s41467-018-03469-52041-1723https://doaj.org/article/48f02766cbcf45fab8fa2795bb729a582018-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03469-5https://doaj.org/toc/2041-1723Cell-free protein synthesis allows for producing proteins without the need of a host organism, thus sparing the researcher experimental hassle. Here, the authors developed a cell-free synthesis method that enables incorporating non-standard amino acids in the product.Rey W. MartinBenjamin J. Des SoyeYong-Chan KwonJennifer KayRoderick G. DavisPaul M. ThomasNatalia I. MajewskaCindy X. ChenRyan D. MarcumMary Grace WeissAshleigh E. StoddartMiriam AmiramArnaz K. Ranji CharnaJaymin R. PatelFarren J. IsaacsNeil L. KelleherSeok Hoon HongMichael C. JewettNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Rey W. Martin
Benjamin J. Des Soye
Yong-Chan Kwon
Jennifer Kay
Roderick G. Davis
Paul M. Thomas
Natalia I. Majewska
Cindy X. Chen
Ryan D. Marcum
Mary Grace Weiss
Ashleigh E. Stoddart
Miriam Amiram
Arnaz K. Ranji Charna
Jaymin R. Patel
Farren J. Isaacs
Neil L. Kelleher
Seok Hoon Hong
Michael C. Jewett
Cell-free protein synthesis from genomically recoded bacteria enables multisite incorporation of noncanonical amino acids
description Cell-free protein synthesis allows for producing proteins without the need of a host organism, thus sparing the researcher experimental hassle. Here, the authors developed a cell-free synthesis method that enables incorporating non-standard amino acids in the product.
format article
author Rey W. Martin
Benjamin J. Des Soye
Yong-Chan Kwon
Jennifer Kay
Roderick G. Davis
Paul M. Thomas
Natalia I. Majewska
Cindy X. Chen
Ryan D. Marcum
Mary Grace Weiss
Ashleigh E. Stoddart
Miriam Amiram
Arnaz K. Ranji Charna
Jaymin R. Patel
Farren J. Isaacs
Neil L. Kelleher
Seok Hoon Hong
Michael C. Jewett
author_facet Rey W. Martin
Benjamin J. Des Soye
Yong-Chan Kwon
Jennifer Kay
Roderick G. Davis
Paul M. Thomas
Natalia I. Majewska
Cindy X. Chen
Ryan D. Marcum
Mary Grace Weiss
Ashleigh E. Stoddart
Miriam Amiram
Arnaz K. Ranji Charna
Jaymin R. Patel
Farren J. Isaacs
Neil L. Kelleher
Seok Hoon Hong
Michael C. Jewett
author_sort Rey W. Martin
title Cell-free protein synthesis from genomically recoded bacteria enables multisite incorporation of noncanonical amino acids
title_short Cell-free protein synthesis from genomically recoded bacteria enables multisite incorporation of noncanonical amino acids
title_full Cell-free protein synthesis from genomically recoded bacteria enables multisite incorporation of noncanonical amino acids
title_fullStr Cell-free protein synthesis from genomically recoded bacteria enables multisite incorporation of noncanonical amino acids
title_full_unstemmed Cell-free protein synthesis from genomically recoded bacteria enables multisite incorporation of noncanonical amino acids
title_sort cell-free protein synthesis from genomically recoded bacteria enables multisite incorporation of noncanonical amino acids
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/48f02766cbcf45fab8fa2795bb729a58
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