Cell-free protein synthesis from genomically recoded bacteria enables multisite incorporation of noncanonical amino acids
Cell-free protein synthesis allows for producing proteins without the need of a host organism, thus sparing the researcher experimental hassle. Here, the authors developed a cell-free synthesis method that enables incorporating non-standard amino acids in the product.
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Nature Portfolio
2018
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oai:doaj.org-article:48f02766cbcf45fab8fa2795bb729a582021-12-02T14:40:30ZCell-free protein synthesis from genomically recoded bacteria enables multisite incorporation of noncanonical amino acids10.1038/s41467-018-03469-52041-1723https://doaj.org/article/48f02766cbcf45fab8fa2795bb729a582018-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03469-5https://doaj.org/toc/2041-1723Cell-free protein synthesis allows for producing proteins without the need of a host organism, thus sparing the researcher experimental hassle. Here, the authors developed a cell-free synthesis method that enables incorporating non-standard amino acids in the product.Rey W. MartinBenjamin J. Des SoyeYong-Chan KwonJennifer KayRoderick G. DavisPaul M. ThomasNatalia I. MajewskaCindy X. ChenRyan D. MarcumMary Grace WeissAshleigh E. StoddartMiriam AmiramArnaz K. Ranji CharnaJaymin R. PatelFarren J. IsaacsNeil L. KelleherSeok Hoon HongMichael C. JewettNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-9 (2018) |
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Science Q |
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Science Q Rey W. Martin Benjamin J. Des Soye Yong-Chan Kwon Jennifer Kay Roderick G. Davis Paul M. Thomas Natalia I. Majewska Cindy X. Chen Ryan D. Marcum Mary Grace Weiss Ashleigh E. Stoddart Miriam Amiram Arnaz K. Ranji Charna Jaymin R. Patel Farren J. Isaacs Neil L. Kelleher Seok Hoon Hong Michael C. Jewett Cell-free protein synthesis from genomically recoded bacteria enables multisite incorporation of noncanonical amino acids |
description |
Cell-free protein synthesis allows for producing proteins without the need of a host organism, thus sparing the researcher experimental hassle. Here, the authors developed a cell-free synthesis method that enables incorporating non-standard amino acids in the product. |
format |
article |
author |
Rey W. Martin Benjamin J. Des Soye Yong-Chan Kwon Jennifer Kay Roderick G. Davis Paul M. Thomas Natalia I. Majewska Cindy X. Chen Ryan D. Marcum Mary Grace Weiss Ashleigh E. Stoddart Miriam Amiram Arnaz K. Ranji Charna Jaymin R. Patel Farren J. Isaacs Neil L. Kelleher Seok Hoon Hong Michael C. Jewett |
author_facet |
Rey W. Martin Benjamin J. Des Soye Yong-Chan Kwon Jennifer Kay Roderick G. Davis Paul M. Thomas Natalia I. Majewska Cindy X. Chen Ryan D. Marcum Mary Grace Weiss Ashleigh E. Stoddart Miriam Amiram Arnaz K. Ranji Charna Jaymin R. Patel Farren J. Isaacs Neil L. Kelleher Seok Hoon Hong Michael C. Jewett |
author_sort |
Rey W. Martin |
title |
Cell-free protein synthesis from genomically recoded bacteria enables multisite incorporation of noncanonical amino acids |
title_short |
Cell-free protein synthesis from genomically recoded bacteria enables multisite incorporation of noncanonical amino acids |
title_full |
Cell-free protein synthesis from genomically recoded bacteria enables multisite incorporation of noncanonical amino acids |
title_fullStr |
Cell-free protein synthesis from genomically recoded bacteria enables multisite incorporation of noncanonical amino acids |
title_full_unstemmed |
Cell-free protein synthesis from genomically recoded bacteria enables multisite incorporation of noncanonical amino acids |
title_sort |
cell-free protein synthesis from genomically recoded bacteria enables multisite incorporation of noncanonical amino acids |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/48f02766cbcf45fab8fa2795bb729a58 |
work_keys_str_mv |
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1718390234850263040 |