The shared genetic architecture between epidemiological and behavioral traits with lung cancer
Abstract The complex polygenic nature of lung cancer is not fully characterized. Our study seeks to identify novel phenotypes associated with lung cancer using cross-trait linkage disequilibrium score regression (LDSR). We measured pairwise genetic correlation (rg) and SNP heritability (h2) between...
Saved in:
Main Authors: | Rowland W. Pettit, Jinyoung Byun, Younghun Han, Quinn T. Ostrom, Jacob Edelson, Kyle M. Walsh, Melissa L. Bondy, Rayjean J. Hung, James D. McKay, Christopher I. Amos |
---|---|
Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2021
|
Subjects: | |
Online Access: | https://doaj.org/article/48f5fa5abd854b65a09e8928448fd58b |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Expanding the genetic architecture of nicotine dependence and its shared genetics with multiple traits
by: Bryan C. Quach, et al.
Published: (2020) -
Modular genome-wide gene expression architecture shared by early traits of osteoporosis and atherosclerosis in the Young Finns Study
by: Binisha H. Mishra, et al.
Published: (2021) -
Bayesian reassessment of the epigenetic architecture of complex traits
by: Daniel Trejo Banos, et al.
Published: (2020) -
The architecture of a shared leadership model for health systems strengthening initiatives led by a U.S.-based academic hospital
by: M.T. Walsh, et al.
Published: (2015) -
Homologous bd oxidases share the same architecture but differ in mechanism
by: Alexander Theßeling, et al.
Published: (2019)