An alcoholic extract of Thuja orientalis L. leaves inhibits autophagy by specifically targeting pro-autophagy PIK3C3/VPS34 complex

Abstract Autophagy is a lysosome-dependent degradation program to maintain cellular homeostasis in response to a variety of stressful conditions, such as long-lived or non-functional subcellular organelles, protein aggregates, nutrient limitation, and virus/bacteria infection. Accordingly, dysregula...

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Bibliographic Details
Main Authors: Juneyoung Jung, Yoomi Chun, Young Pyo Jang, Myung Sook Oh, Jeong Hee Kim, Joungmok Kim
Format: article
Language:EN
Published: Nature Portfolio 2021
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Online Access:https://doaj.org/article/48f6c0b15b1649159dfc2777e8bad3c0
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