Association Between Body Composition and Frailty in Elder Inpatients

Liyu Xu,1 Jie Zhang,2 Shanshan Shen,1 Xiufang Hong,1 Xingkun Zeng,1 Yinghong Yang,1 Zixia Liu,1 Lingyan Chen,1 Xujiao Chen1 1Department of Geriatrics, Zhejiang Hospital, Hangzhou 310013, People’s Republic of China; 2Department of Dentistry, Zhejiang Hospital, Hangzhou 310013, People&rs...

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Autores principales:	Xu L, Zhang J, Shen S, Hong X, Zeng X, Yang Y, Liu Z, Chen L, Chen X
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2020
Materias:	frailty elderly skeletal muscle mass body fat mass Geriatrics RC952-954.6
Acceso en línea:	https://doaj.org/article/48f89389cc59422a8ad01c3012592c4d
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spelling	oai:doaj.org-article:48f89389cc59422a8ad01c3012592c4d2021-12-02T13:14:03ZAssociation Between Body Composition and Frailty in Elder Inpatients1178-1998https://doaj.org/article/48f89389cc59422a8ad01c3012592c4d2020-03-01T00:00:00Zhttps://www.dovepress.com/association-between-body-composition-and-frailty-in-elder-inpatients-peer-reviewed-article-CIAhttps://doaj.org/toc/1178-1998Liyu Xu,1 Jie Zhang,2 Shanshan Shen,1 Xiufang Hong,1 Xingkun Zeng,1 Yinghong Yang,1 Zixia Liu,1 Lingyan Chen,1 Xujiao Chen1 1Department of Geriatrics, Zhejiang Hospital, Hangzhou 310013, People’s Republic of China; 2Department of Dentistry, Zhejiang Hospital, Hangzhou 310013, People’s Republic of ChinaCorrespondence: Xujiao ChenDepartment of Geriatrics, Zhejiang Hospital, Lingyin Road #12, Hangzhou 310013, People’s Republic of ChinaTel +86 18069897567Fax +86 0571 87985100Email lily197459@163.comPurpose: The study aimed to investigate the association between body composition and frailty in elder inpatients.Patients and Methods: This is a cross-sectional study including 656 elder inpatients (275 females and 381 males) aged ≥ 65 years, from department of geriatrics of Zhejiang Hospital between January 2018 and March 2019. Sociodemographic, health-related data and anthropometric measurements were evaluated. Body composition was assessed by bioimpedance analysis (BIA), mainly including skeletal muscle mass, body fat mass, total body water, fat-free mass,percent body fat, basal metabolic rate. Frailty was assessed by Clinical Frailty Scale (CFS). Univariate logistic regression was used to analyze the association between body composition and frailty.Results: Frailty was present in 43.9% of the participants. Frail inpatients showed higher waist circumference, body fat mass and percent body fat, non-frail inpatients showed greater upper arm circumference, calf circumference, skeletal muscle mass, total body water, fat-free mass and basal metabolic rate. Subjects with underweight (body mass index (BMI)< 18.5 kg/m2; odds ratio (OR),  95% confidence interval (CI)=4.146 (1.286– 13.368) P=0.017) and those with high waist circumference (OR 95% CI=1.428 (0.584– 3.491) P< 0.001), body fat mass (OR, 95% CI=1.143 (0.892– 1.315) P< 0.001) presented a higher risk of frailty compared to normal subjects. Skeletal muscle mass (OR; 95% CI=0.159 (0.064– 0.396) P< 0.001) was a protective factor for frailty.Conclusion: Frailty in elder Chinese inpatients was characterized by a body composition phenotype with underweight, high waist circumference, low skeletal muscle mass and high body fat mass. Underweight, abdominal obesity and sarcopenic obesity may, therefore, be targets for intervention of frailty.Keywords: frailty, elderly, skeletal muscle mass, body fat massXu LZhang JShen SHong XZeng XYang YLiu ZChen LChen XDove Medical Pressarticlefrailtyelderlyskeletal muscle massbody fat massGeriatricsRC952-954.6ENClinical Interventions in Aging, Vol Volume 15, Pp 313-320 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	frailty elderly skeletal muscle mass body fat mass Geriatrics RC952-954.6
spellingShingle	frailty elderly skeletal muscle mass body fat mass Geriatrics RC952-954.6 Xu L Zhang J Shen S Hong X Zeng X Yang Y Liu Z Chen L Chen X Association Between Body Composition and Frailty in Elder Inpatients
description	Liyu Xu,1 Jie Zhang,2 Shanshan Shen,1 Xiufang Hong,1 Xingkun Zeng,1 Yinghong Yang,1 Zixia Liu,1 Lingyan Chen,1 Xujiao Chen1 1Department of Geriatrics, Zhejiang Hospital, Hangzhou 310013, People’s Republic of China; 2Department of Dentistry, Zhejiang Hospital, Hangzhou 310013, People’s Republic of ChinaCorrespondence: Xujiao ChenDepartment of Geriatrics, Zhejiang Hospital, Lingyin Road #12, Hangzhou 310013, People’s Republic of ChinaTel +86 18069897567Fax +86 0571 87985100Email lily197459@163.comPurpose: The study aimed to investigate the association between body composition and frailty in elder inpatients.Patients and Methods: This is a cross-sectional study including 656 elder inpatients (275 females and 381 males) aged ≥ 65 years, from department of geriatrics of Zhejiang Hospital between January 2018 and March 2019. Sociodemographic, health-related data and anthropometric measurements were evaluated. Body composition was assessed by bioimpedance analysis (BIA), mainly including skeletal muscle mass, body fat mass, total body water, fat-free mass,percent body fat, basal metabolic rate. Frailty was assessed by Clinical Frailty Scale (CFS). Univariate logistic regression was used to analyze the association between body composition and frailty.Results: Frailty was present in 43.9% of the participants. Frail inpatients showed higher waist circumference, body fat mass and percent body fat, non-frail inpatients showed greater upper arm circumference, calf circumference, skeletal muscle mass, total body water, fat-free mass and basal metabolic rate. Subjects with underweight (body mass index (BMI)< 18.5 kg/m2; odds ratio (OR),  95% confidence interval (CI)=4.146 (1.286– 13.368) P=0.017) and those with high waist circumference (OR 95% CI=1.428 (0.584– 3.491) P< 0.001), body fat mass (OR, 95% CI=1.143 (0.892– 1.315) P< 0.001) presented a higher risk of frailty compared to normal subjects. Skeletal muscle mass (OR; 95% CI=0.159 (0.064– 0.396) P< 0.001) was a protective factor for frailty.Conclusion: Frailty in elder Chinese inpatients was characterized by a body composition phenotype with underweight, high waist circumference, low skeletal muscle mass and high body fat mass. Underweight, abdominal obesity and sarcopenic obesity may, therefore, be targets for intervention of frailty.Keywords: frailty, elderly, skeletal muscle mass, body fat mass
format	article
author	Xu L Zhang J Shen S Hong X Zeng X Yang Y Liu Z Chen L Chen X
author_facet	Xu L Zhang J Shen S Hong X Zeng X Yang Y Liu Z Chen L Chen X
author_sort	Xu L
title	Association Between Body Composition and Frailty in Elder Inpatients
title_short	Association Between Body Composition and Frailty in Elder Inpatients
title_full	Association Between Body Composition and Frailty in Elder Inpatients
title_fullStr	Association Between Body Composition and Frailty in Elder Inpatients
title_full_unstemmed	Association Between Body Composition and Frailty in Elder Inpatients
title_sort	association between body composition and frailty in elder inpatients
publisher	Dove Medical Press
publishDate	2020
url	https://doaj.org/article/48f89389cc59422a8ad01c3012592c4d
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Association Between Body Composition and Frailty in Elder Inpatients

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