Regulation of the Fanconi Anemia DNA Repair Pathway by Phosphorylation and Monoubiquitination

The Fanconi anemia (FA) DNA repair pathway coordinates a faithful repair mechanism for stalled DNA replication forks caused by factors such as DNA interstrand crosslinks (ICLs) or replication stress. An important role of FA pathway activation is initiated by monoubiquitination of FANCD2 and its bind...

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Autor principal: Masamichi Ishiai
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
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ATM
Acceso en línea:https://doaj.org/article/48fb5e63ca36405db9f5bb01e9b0345c
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