Innate immune evasion revealed in a colorectal zebrafish xenograft model
Zebrafish has emerged as an important vertebrate model to study tumor biology and immune response. Here, using a zebrafish xenograft model, the authors show that the engraftment capacity of human colorectal cancer cell lines is influenced by innate immune response and immunoediting.
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Nature Portfolio
2021
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oai:doaj.org-article:48fd4343553143d69dfb78cdaf6ab9392021-12-02T14:03:50ZInnate immune evasion revealed in a colorectal zebrafish xenograft model10.1038/s41467-021-21421-y2041-1723https://doaj.org/article/48fd4343553143d69dfb78cdaf6ab9392021-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21421-yhttps://doaj.org/toc/2041-1723Zebrafish has emerged as an important vertebrate model to study tumor biology and immune response. Here, using a zebrafish xenograft model, the authors show that the engraftment capacity of human colorectal cancer cell lines is influenced by innate immune response and immunoediting.Vanda PóvoaCátia Rebelo de AlmeidaMariana Maia-GilDaniel SobralMicaela DominguesMayra Martinez-LopezMiguel de Almeida FuzetaCarlos SilvaAna Rita GrossoRita FiorNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-15 (2021) |
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Science Q Vanda Póvoa Cátia Rebelo de Almeida Mariana Maia-Gil Daniel Sobral Micaela Domingues Mayra Martinez-Lopez Miguel de Almeida Fuzeta Carlos Silva Ana Rita Grosso Rita Fior Innate immune evasion revealed in a colorectal zebrafish xenograft model |
description |
Zebrafish has emerged as an important vertebrate model to study tumor biology and immune response. Here, using a zebrafish xenograft model, the authors show that the engraftment capacity of human colorectal cancer cell lines is influenced by innate immune response and immunoediting. |
format |
article |
author |
Vanda Póvoa Cátia Rebelo de Almeida Mariana Maia-Gil Daniel Sobral Micaela Domingues Mayra Martinez-Lopez Miguel de Almeida Fuzeta Carlos Silva Ana Rita Grosso Rita Fior |
author_facet |
Vanda Póvoa Cátia Rebelo de Almeida Mariana Maia-Gil Daniel Sobral Micaela Domingues Mayra Martinez-Lopez Miguel de Almeida Fuzeta Carlos Silva Ana Rita Grosso Rita Fior |
author_sort |
Vanda Póvoa |
title |
Innate immune evasion revealed in a colorectal zebrafish xenograft model |
title_short |
Innate immune evasion revealed in a colorectal zebrafish xenograft model |
title_full |
Innate immune evasion revealed in a colorectal zebrafish xenograft model |
title_fullStr |
Innate immune evasion revealed in a colorectal zebrafish xenograft model |
title_full_unstemmed |
Innate immune evasion revealed in a colorectal zebrafish xenograft model |
title_sort |
innate immune evasion revealed in a colorectal zebrafish xenograft model |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/48fd4343553143d69dfb78cdaf6ab939 |
work_keys_str_mv |
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