Innate immune evasion revealed in a colorectal zebrafish xenograft model

Zebrafish has emerged as an important vertebrate model to study tumor biology and immune response. Here, using a zebrafish xenograft model, the authors show that the engraftment capacity of human colorectal cancer cell lines is influenced by innate immune response and immunoediting.

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Autores principales: Vanda Póvoa, Cátia Rebelo de Almeida, Mariana Maia-Gil, Daniel Sobral, Micaela Domingues, Mayra Martinez-Lopez, Miguel de Almeida Fuzeta, Carlos Silva, Ana Rita Grosso, Rita Fior
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/48fd4343553143d69dfb78cdaf6ab939
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spelling oai:doaj.org-article:48fd4343553143d69dfb78cdaf6ab9392021-12-02T14:03:50ZInnate immune evasion revealed in a colorectal zebrafish xenograft model10.1038/s41467-021-21421-y2041-1723https://doaj.org/article/48fd4343553143d69dfb78cdaf6ab9392021-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21421-yhttps://doaj.org/toc/2041-1723Zebrafish has emerged as an important vertebrate model to study tumor biology and immune response. Here, using a zebrafish xenograft model, the authors show that the engraftment capacity of human colorectal cancer cell lines is influenced by innate immune response and immunoediting.Vanda PóvoaCátia Rebelo de AlmeidaMariana Maia-GilDaniel SobralMicaela DominguesMayra Martinez-LopezMiguel de Almeida FuzetaCarlos SilvaAna Rita GrossoRita FiorNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Vanda Póvoa
Cátia Rebelo de Almeida
Mariana Maia-Gil
Daniel Sobral
Micaela Domingues
Mayra Martinez-Lopez
Miguel de Almeida Fuzeta
Carlos Silva
Ana Rita Grosso
Rita Fior
Innate immune evasion revealed in a colorectal zebrafish xenograft model
description Zebrafish has emerged as an important vertebrate model to study tumor biology and immune response. Here, using a zebrafish xenograft model, the authors show that the engraftment capacity of human colorectal cancer cell lines is influenced by innate immune response and immunoediting.
format article
author Vanda Póvoa
Cátia Rebelo de Almeida
Mariana Maia-Gil
Daniel Sobral
Micaela Domingues
Mayra Martinez-Lopez
Miguel de Almeida Fuzeta
Carlos Silva
Ana Rita Grosso
Rita Fior
author_facet Vanda Póvoa
Cátia Rebelo de Almeida
Mariana Maia-Gil
Daniel Sobral
Micaela Domingues
Mayra Martinez-Lopez
Miguel de Almeida Fuzeta
Carlos Silva
Ana Rita Grosso
Rita Fior
author_sort Vanda Póvoa
title Innate immune evasion revealed in a colorectal zebrafish xenograft model
title_short Innate immune evasion revealed in a colorectal zebrafish xenograft model
title_full Innate immune evasion revealed in a colorectal zebrafish xenograft model
title_fullStr Innate immune evasion revealed in a colorectal zebrafish xenograft model
title_full_unstemmed Innate immune evasion revealed in a colorectal zebrafish xenograft model
title_sort innate immune evasion revealed in a colorectal zebrafish xenograft model
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/48fd4343553143d69dfb78cdaf6ab939
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