Multi-tumor analysis of cancer-stroma interactomes of patient-derived xenografts unveils the unique homeostatic process in renal cell carcinomas

Multi-tumor analysis of cancer-stroma interactomes of patient-derived xenografts unveils the unique homeostatic process in renal cell carcinomas

Summary: The patient-derived xenograft (PDX) model is a versatile tool used to study the tumor microenvironment (TME). However, limited studies have described multi-tumor PDX screening strategies to detect hub regulators during cancer-stroma interaction. Transcriptomes of cancer (human) and stroma (...

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Autores principales: Kuniyo Sueyoshi, Daisuke Komura, Hiroto Katoh, Asami Yamamoto, Takumi Onoyama, Tsuyoshi Chijiwa, Takayuki Isagawa, Mariko Tanaka, Hiroshi Suemizu, Masato Nakamura, Yohei Miyagi, Hiroyuki Aburatani, Shumpei Ishikawa
Formato: article
Lenguaje:EN
Publicado: Elsevier 2021
Materias:
Cancer systems biology
Cancer
Science
Q
Acceso en línea:https://doaj.org/article/49010a93e08142cb8533d7ed48938bcf
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