Telomerase subunit Est2 marks internal sites that are prone to accumulate DNA damage
Abstract Background The main function of telomerase is at the telomeres but under adverse conditions telomerase can bind to internal regions causing deleterious effects as observed in cancer cells. Results By mapping the global occupancy of the catalytic subunit of telomerase (Est2) in the budding y...
Guardado en:
Autores principales: | Satyaprakash Pandey, Mona Hajikazemi, Theresa Zacheja, Stephanie Schalbetter, Jonathan Baxter, Victor Guryev, Andreas Hofmann, Dieter W. Heermann, Stefan A. Juranek, Katrin Paeschke |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
BMC
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/49015b42ea7c44bda95a827b3a9a2668 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Evaluation of an oral telomerase activator for early age-related macular degeneration - a pilot study
por: Dow CT, et al.
Publicado: (2016) -
Molecular imaging of telomerase and the enzyme activity-triggered drug release by using a conformation-switchable nanoprobe in cancerous cells
por: Hai Shi, et al.
Publicado: (2018) -
Yes-associated protein 1 as a prognostic biomarker and its correlation with telomerase in various cancers
por: Hye-Ran Kim, et al.
Publicado: (2021) -
Telomerase-positive circulating tumor cells are associated with poor prognosis via a neutrophil-mediated inflammatory immune environment in glioma
por: Wen Zhang, et al.
Publicado: (2021) -
Cell Cycle, Telomeres, and Telomerase in <i>Leishmania</i> spp.: What Do We Know So Far?
por: Luiz H. C. Assis, et al.
Publicado: (2021)