Telomerase subunit Est2 marks internal sites that are prone to accumulate DNA damage

Abstract Background The main function of telomerase is at the telomeres but under adverse conditions telomerase can bind to internal regions causing deleterious effects as observed in cancer cells. Results By mapping the global occupancy of the catalytic subunit of telomerase (Est2) in the budding y...

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Auteurs principaux: Satyaprakash Pandey, Mona Hajikazemi, Theresa Zacheja, Stephanie Schalbetter, Jonathan Baxter, Victor Guryev, Andreas Hofmann, Dieter W. Heermann, Stefan A. Juranek, Katrin Paeschke
Format: article
Langue:EN
Publié: BMC 2021
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Accès en ligne:https://doaj.org/article/49015b42ea7c44bda95a827b3a9a2668
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