Identification of Candida glabrata genes involved in pH modulation and modification of the phagosomal environment in macrophages.

Identification of Candida glabrata genes involved in pH modulation and modification of the phagosomal environment in macrophages.

Candida glabrata currently ranks as the second most frequent cause of invasive candidiasis. Our previous work has shown that C. glabrata is adapted to intracellular survival in macrophages and replicates within non-acidified late endosomal-stage phagosomes. In contrast, heat killed yeasts are found...

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Autores principales: Lydia Kasper, Katja Seider, Franziska Gerwien, Stefanie Allert, Sascha Brunke, Tobias Schwarzmüller, Lauren Ames, Cristina Zubiria-Barrera, Michael K Mansour, Ulrike Becken, Dagmar Barz, Jatin M Vyas, Norbert Reiling, Albert Haas, Ken Haynes, Karl Kuchler, Bernhard Hube
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/49034b090187471099caa478a807232e
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